> For the complete documentation index, see [llms.txt](https://whve.gitbook.io/riskad/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://whve.gitbook.io/riskad/mr-base-database/calculation-results-of-four-methods.md). # Calculation results of four methods | exposure | method | nsnp | b | se | pval | | ------------------------------------------------------------------------------------ | ------------------------- | ---- | ------------ | ----------- | ----------- | | Adiponectin \|\| id:1 | Inverse variance weighted | 11 | -0.182645561 | 0.134259093 | 0.173704577 | | Adiponectin \|\| id:1 | MR Egger | 11 | -0.293687183 | 0.223442923 | 0.221229547 | | Adiponectin \|\| id:1 | Weighted median | 11 | -0.177684586 | 0.132570917 | 0.180148358 | | Adiponectin \|\| id:1 | Weighted mode | 11 | -0.208389056 | 0.144046257 | 0.178593651 | | Crohn's disease \|\| id:10 | Inverse variance weighted | 98 | -0.028534491 | 0.016115088 | 0.076615727 | | Crohn's disease \|\| id:10 | MR Egger | 98 | -0.020325301 | 0.034832517 | 0.560915007 | | Crohn's disease \|\| id:10 | Weighted median | 98 | -0.017859562 | 0.020331036 | 0.379705875 | | Crohn's disease \|\| id:10 | Weighted mode | 98 | -0.028730005 | 0.02465666 | 0.246794401 | | Depressive symptoms \|\| id:1000 | Wald ratio | 1 | -0.596774194 | 0.664516129 | 0.369154494 | | Years of schooling \|\| id:1001 | Inverse variance weighted | 64 | -0.529487966 | 0.139348812 | 0.000144853 | | Years of schooling \|\| id:1001 | MR Egger | 64 | -1.842941839 | 0.739306116 | 0.015358965 | | Years of schooling \|\| id:1001 | Weighted median | 64 | -0.621410733 | 0.184345067 | 0.000749202 | | Years of schooling \|\| id:1001 | Weighted mode | 64 | -1.002521699 | 0.429021179 | 0.022644585 | | Leptin \|\| id:1002 | Wald ratio | 1 | 0.553691275 | 0.543624161 | 0.308431605 | | Percent emphysema \|\| id:1005 | Wald ratio | 1 | 0.295825771 | 0.284936479 | 0.299169244 | | Mean platelet volume \|\| id:1006 | Inverse variance weighted | 22 | 0.209658878 | 0.333698535 | 0.529815109 | | Mean platelet volume \|\| id:1006 | MR Egger | 22 | 0.984040373 | 0.785527842 | 0.224760396 | | Mean platelet volume \|\| id:1006 | Weighted median | 22 | 0.502404411 | 0.459935593 | 0.274685247 | | Mean platelet volume \|\| id:1006 | Weighted mode | 22 | 0.532212169 | 0.495041885 | 0.294534197 | | Neuroticism \|\| id:1007 | Inverse variance weighted | 8 | -0.226641986 | 0.295035897 | 0.442377615 | | Neuroticism \|\| id:1007 | MR Egger | 8 | -0.788673527 | 2.485044984 | 0.761718142 | | Neuroticism \|\| id:1007 | Weighted median | 8 | 0.097904846 | 0.372316013 | 0.79258011 | | Neuroticism \|\| id:1007 | Weighted mode | 8 | 0.233210773 | 0.480619505 | 0.642330758 | | Platelet count \|\| id:1008 | Inverse variance weighted | 31 | -0.000723321 | 0.000875264 | 0.408575304 | | Platelet count \|\| id:1008 | MR Egger | 31 | -0.001915243 | 0.002608178 | 0.468648727 | | Platelet count \|\| id:1008 | Weighted median | 31 | -0.001118024 | 0.001281972 | 0.383146961 | | Platelet count \|\| id:1008 | Weighted mode | 31 | -0.001164828 | 0.002183642 | 0.597663879 | | Subjective well being \|\| id:1009 | Wald ratio | 1 | -0.004761905 | 0.857142857 | 0.995567331 | | Plasma cortisol \|\| id:1012 | Wald ratio | 1 | 0.059960156 | 0.187617261 | 0.749280954 | | C-reactive protein \|\| id:1015 | Inverse variance weighted | 3 | 0.244753443 | 0.107812241 | 0.023196524 | | C-reactive protein \|\| id:1015 | MR Egger | 3 | 0.177401363 | 0.436104463 | 0.754046411 | | C-reactive protein \|\| id:1015 | Weighted median | 3 | 0.233014906 | 0.126869712 | 0.066261989 | | C-reactive protein \|\| id:1015 | Weighted mode | 3 | 0.229315451 | 0.148597976 | 0.262755294 | | Oligoclonal band status \|\| id:1016 | Wald ratio | 1 | 0.117240686 | 0.042740481 | 0.00608653 | | Subjective well being \|\| id:1018 | Wald ratio | 1 | -0.004543307 | 0.817795224 | 0.995567331 | | Migraine in bipolar disorder \|\| id:1019 | Wald ratio | 1 | -0.037538427 | 0.03470219 | 0.279372177 | | Multiple sclerosis \|\| id:1024 | Inverse variance weighted | 22 | -0.031580988 | 0.028735918 | 0.271764806 | | Multiple sclerosis \|\| id:1024 | MR Egger | 22 | -0.17023043 | 0.15237878 | 0.277170164 | | Multiple sclerosis \|\| id:1024 | Weighted median | 22 | -0.000551826 | 0.040185807 | 0.989043909 | | Multiple sclerosis \|\| id:1024 | Weighted mode | 22 | 0.030373035 | 0.072483092 | 0.67944481 | | Multiple sclerosis \|\| id:1025 | Inverse variance weighted | 37 | -0.022936363 | 0.023860235 | 0.33641148 | | Multiple sclerosis \|\| id:1025 | MR Egger | 37 | -0.020231454 | 0.078431551 | 0.797955886 | | Multiple sclerosis \|\| id:1025 | Weighted median | 37 | -0.047942242 | 0.032415472 | 0.139142302 | | Multiple sclerosis \|\| id:1025 | Weighted mode | 37 | -0.014509418 | 0.051915106 | 0.781473257 | | Height \|\| id:1034 | Inverse variance weighted | 4 | -0.137319633 | 0.106810227 | 0.198568297 | | Height \|\| id:1034 | MR Egger | 4 | 0.659868273 | 2.446470376 | 0.812654271 | | Height \|\| id:1034 | Weighted median | 4 | -0.152369723 | 0.124981272 | 0.222790891 | | Height \|\| id:1034 | Weighted mode | 4 | -0.206258636 | 0.168744794 | 0.308864208 | | Difference in height between childhood and adulthood \|\| id:1037 | Wald ratio | 1 | 0.102508631 | 0.199955107 | 0.608190415 | | Difference in height between adolescence and adulthood \|\| id:1040 | Wald ratio | 1 | -0.170651721 | 0.232953143 | 0.46382797 | | Intracranial volume \|\| id:1041 | Wald ratio | 1 | 3.01E-06 | 1.25E-06 | 0.015795248 | | Amygdala volume \|\| id:1043 | Wald ratio | 1 | 9.72E-06 | 0.001225253 | 0.993667649 | | Hippocampus volume \|\| id:1045 | Inverse variance weighted | 2 | 0.000947155 | 0.00040489 | 0.019320529 | | Putamen volume \|\| id:1047 | Inverse variance weighted | 4 | -7.79E-05 | 0.000187417 | 0.677523211 | | Putamen volume \|\| id:1047 | MR Egger | 4 | 0.000126083 | 0.000999602 | 0.911163296 | | Putamen volume \|\| id:1047 | Weighted median | 4 | -0.000128781 | 0.000213429 | 0.546249055 | | Putamen volume \|\| id:1047 | Weighted mode | 4 | -0.000145145 | 0.000267602 | 0.625246495 | | Iron \|\| id:1049 | Inverse variance weighted | 3 | -0.032347745 | 0.058841429 | 0.582494714 | | Iron \|\| id:1049 | MR Egger | 3 | -0.047828432 | 0.117416321 | 0.753743759 | | Iron \|\| id:1049 | Weighted median | 3 | -0.031647597 | 0.063551912 | 0.61849796 | | Iron \|\| id:1049 | Weighted mode | 3 | -0.021581144 | 0.072566973 | 0.794210133 | | Ferritin \|\| id:1050 | Inverse variance weighted | 4 | 0.027403643 | 0.176721368 | 0.876768539 | | Ferritin \|\| id:1050 | MR Egger | 4 | -0.230262111 | 0.359904999 | 0.587820082 | | Ferritin \|\| id:1050 | Weighted median | 4 | -0.056351045 | 0.131013304 | 0.667110556 | | Ferritin \|\| id:1050 | Weighted mode | 4 | -0.06922912 | 0.124036642 | 0.61569891 | | Transferrin Saturation \|\| id:1051 | Inverse variance weighted | 3 | -0.025070048 | 0.045155118 | 0.578758976 | | Transferrin Saturation \|\| id:1051 | MR Egger | 3 | -0.035762849 | 0.076823302 | 0.722633779 | | Transferrin Saturation \|\| id:1051 | Weighted median | 3 | -0.026352666 | 0.049301284 | 0.592979811 | | Transferrin Saturation \|\| id:1051 | Weighted mode | 3 | -0.027184329 | 0.050116834 | 0.641889046 | | Transferrin \|\| id:1052 | Inverse variance weighted | 7 | 0.010485392 | 0.031530259 | 0.739473885 | | Transferrin \|\| id:1052 | MR Egger | 7 | 0.011235797 | 0.044282161 | 0.809805987 | | Transferrin \|\| id:1052 | Weighted median | 7 | 0.010638095 | 0.03419213 | 0.755704062 | | Transferrin \|\| id:1052 | Weighted mode | 7 | 0.008803784 | 0.032143151 | 0.793351738 | | Gout \|\| id:1054 | Inverse variance weighted | 2 | 0.02325214 | 0.029949503 | 0.437525737 | | Urate \|\| id:1055 | Inverse variance weighted | 24 | 0.087826794 | 0.037518233 | 0.01923682 | | Urate \|\| id:1055 | MR Egger | 24 | 0.138585247 | 0.060538952 | 0.032031705 | | Urate \|\| id:1055 | Weighted median | 24 | 0.100984928 | 0.051657619 | 0.050596132 | | Urate \|\| id:1055 | Weighted mode | 24 | 0.104382481 | 0.046988294 | 0.036443393 | | Heart rate \|\| id:1056 | Inverse variance weighted | 15 | 0.008341862 | 0.010612022 | 0.431822609 | | Heart rate \|\| id:1056 | MR Egger | 15 | 0.034081058 | 0.042953883 | 0.441767072 | | Heart rate \|\| id:1056 | Weighted median | 15 | -4.96E-05 | 0.014584389 | 0.99728588 | | Heart rate \|\| id:1056 | Weighted mode | 15 | -0.007871627 | 0.021563139 | 0.720529738 | | Celiac disease \|\| id:1058 | Inverse variance weighted | 11 | -0.015910284 | 0.019698182 | 0.419261476 | | Celiac disease \|\| id:1058 | MR Egger | 11 | 0.008914869 | 0.02776003 | 0.755436084 | | Celiac disease \|\| id:1058 | Weighted median | 11 | -0.002915122 | 0.023661399 | 0.901947456 | | Celiac disease \|\| id:1058 | Weighted mode | 11 | -0.005132036 | 0.022073698 | 0.820842377 | | Celiac disease \|\| id:1059 | Inverse variance weighted | 11 | -0.037722498 | 0.024695283 | 0.126632161 | | Celiac disease \|\| id:1059 | MR Egger | 11 | -0.090717895 | 0.089973177 | 0.339659007 | | Celiac disease \|\| id:1059 | Weighted median | 11 | -0.042601174 | 0.031422397 | 0.175176095 | | Celiac disease \|\| id:1059 | Weighted mode | 11 | -0.038265045 | 0.048110676 | 0.444875452 | | Celiac disease \|\| id:1060 | Inverse variance weighted | 7 | -0.015241933 | 0.030594859 | 0.618352891 | | Celiac disease \|\| id:1060 | MR Egger | 7 | -0.168498243 | 0.248248754 | 0.527436652 | | Celiac disease \|\| id:1060 | Weighted median | 7 | -0.002067233 | 0.037901889 | 0.956503592 | | Celiac disease \|\| id:1060 | Weighted mode | 7 | -0.003111455 | 0.056945879 | 0.958200136 | | Sitting height ratio \|\| id:1069 | Wald ratio | 1 | 0.042307692 | 0.153076923 | 0.78225475 | | Sitting height ratio \|\| id:1070 | Inverse variance weighted | 4 | -0.051049201 | 0.129794887 | 0.69409296 | | Sitting height ratio \|\| id:1070 | MR Egger | 4 | 0.634450906 | 1.132428542 | 0.631687832 | | Sitting height ratio \|\| id:1070 | Weighted median | 4 | -0.020923568 | 0.148309391 | 0.887806324 | | Sitting height ratio \|\| id:1070 | Weighted mode | 4 | -0.001323879 | 0.180325357 | 0.994603208 | | Copper \|\| id:1073 | Inverse variance weighted | 2 | -0.144584218 | 0.072598111 | 0.04641826 | | Selenium \|\| id:1077 | Wald ratio | 1 | -0.011698113 | 0.072075472 | 0.871066729 | | Zinc \|\| id:1079 | Inverse variance weighted | 2 | -0.014035699 | 0.075691812 | 0.85289006 | | Birth weight \|\| id:1083 | Inverse variance weighted | 41 | -0.057557531 | 0.096500639 | 0.550876548 | | Birth weight \|\| id:1083 | MR Egger | 41 | -0.093800206 | 0.333123392 | 0.779755855 | | Birth weight \|\| id:1083 | Weighted median | 41 | -0.111184127 | 0.138561157 | 0.422310537 | | Birth weight \|\| id:1083 | Weighted mode | 41 | -0.028932208 | 0.254938316 | 0.910212091 | | Birth weight \|\| id:1084 | Inverse variance weighted | 48 | -0.144537809 | 0.101582015 | 0.154774394 | | Birth weight \|\| id:1084 | MR Egger | 48 | 0.09204626 | 0.359923663 | 0.799293072 | | Birth weight \|\| id:1084 | Weighted median | 48 | -0.180084158 | 0.13686626 | 0.188252134 | | Birth weight \|\| id:1084 | Weighted mode | 48 | -0.105926752 | 0.244113163 | 0.666328485 | | Amyotrophic lateral sclerosis \|\| id:1085 | Inverse variance weighted | 5 | 0.315865621 | 0.294381301 | 0.283279522 | | Amyotrophic lateral sclerosis \|\| id:1085 | MR Egger | 5 | -0.292353175 | 1.070043267 | 0.802416084 | | Amyotrophic lateral sclerosis \|\| id:1085 | Weighted median | 5 | 0.147073794 | 0.356257927 | 0.679731511 | | Amyotrophic lateral sclerosis \|\| id:1085 | Weighted mode | 5 | 0.089742175 | 0.417307512 | 0.840247481 | | Amyotrophic lateral sclerosis \|\| id:1086 | Inverse variance weighted | 3 | 0.055945578 | 0.076437849 | 0.464223885 | | Amyotrophic lateral sclerosis \|\| id:1086 | MR Egger | 3 | -0.094639097 | 0.366435118 | 0.839096477 | | Amyotrophic lateral sclerosis \|\| id:1086 | Weighted median | 3 | 0.025187756 | 0.085701185 | 0.768832736 | | Amyotrophic lateral sclerosis \|\| id:1086 | Weighted mode | 3 | 0.014513317 | 0.101300579 | 0.899208826 | | Chronotype \|\| id:1087 | Inverse variance weighted | 8 | 0.156926926 | 0.356880924 | 0.660141445 | | Chronotype \|\| id:1087 | MR Egger | 8 | 1.590672993 | 1.01629519 | 0.168580608 | | Chronotype \|\| id:1087 | Weighted median | 8 | 0.077105817 | 0.329355088 | 0.814898411 | | Chronotype \|\| id:1087 | Weighted mode | 8 | 0.05772089 | 0.492432976 | 0.9099814 | | Sleep duration \|\| id:1088 | Inverse variance weighted | 2 | -0.134937833 | 0.391686527 | 0.730466795 | | Childhood obesity \|\| id:1096 | Inverse variance weighted | 5 | -0.046724284 | 0.044763713 | 0.296578756 | | Childhood obesity \|\| id:1096 | MR Egger | 5 | -0.534422108 | 0.300400958 | 0.173286556 | | Childhood obesity \|\| id:1096 | Weighted median | 5 | 0.014587823 | 0.055218225 | 0.791637424 | | Childhood obesity \|\| id:1096 | Weighted mode | 5 | 0.025037742 | 0.07604502 | 0.758485978 | | Microalbuminuria \|\| id:1097 | Wald ratio | 1 | 0.01 | 0.1195 | 0.933309262 | | Crohn's disease \|\| id:11 | Inverse variance weighted | 9 | -0.015011572 | 0.015350144 | 0.328102332 | | Crohn's disease \|\| id:11 | MR Egger | 9 | -0.02721687 | 0.037123487 | 0.487290576 | | Crohn's disease \|\| id:11 | Weighted median | 9 | -0.012931734 | 0.017958324 | 0.471465306 | | Crohn's disease \|\| id:11 | Weighted mode | 9 | -0.015173546 | 0.018708148 | 0.440787939 | | Chronic kidney disease \|\| id:1102 | Inverse variance weighted | 4 | 0.027982904 | 0.062122103 | 0.65238597 | | Chronic kidney disease \|\| id:1102 | MR Egger | 4 | -0.035179571 | 0.218041192 | 0.886648084 | | Chronic kidney disease \|\| id:1102 | Weighted median | 4 | 0.029185574 | 0.076135195 | 0.701468574 | | Chronic kidney disease \|\| id:1102 | Weighted mode | 4 | 0.015872683 | 0.086244576 | 0.865717369 | | Serum creatinine (eGFRcrea) \|\| id:1103 | Wald ratio | 1 | 0.065384615 | 0.780769231 | 0.933260098 | | Serum creatinine (eGFRcrea) \|\| id:1104 | Inverse variance weighted | 37 | 0.419117345 | 0.415492064 | 0.313106408 | | Serum creatinine (eGFRcrea) \|\| id:1104 | MR Egger | 37 | -1.686533238 | 1.447419141 | 0.251817972 | | Serum creatinine (eGFRcrea) \|\| id:1104 | Weighted median | 37 | 0.216313048 | 0.535120721 | 0.686041948 | | Serum creatinine (eGFRcrea) \|\| id:1104 | Weighted mode | 37 | 0.150509057 | 0.801969415 | 0.852185793 | | Serum creatinine (eGFRcrea) \|\| id:1105 | Inverse variance weighted | 37 | 0.440086038 | 0.377727485 | 0.243983076 | | Serum creatinine (eGFRcrea) \|\| id:1105 | MR Egger | 37 | -1.632434554 | 1.24390894 | 0.1979462 | | Serum creatinine (eGFRcrea) \|\| id:1105 | Weighted median | 37 | 0.129039828 | 0.536836982 | 0.810042967 | | Serum creatinine (eGFRcrea) \|\| id:1105 | Weighted mode | 37 | 0.031377084 | 0.854661789 | 0.970916776 | | Serum cystatin C (eGFRcys) \|\| id:1106 | Inverse variance weighted | 5 | -0.053364467 | 0.259327728 | 0.836962743 | | Serum cystatin C (eGFRcys) \|\| id:1106 | MR Egger | 5 | -0.566019071 | 0.359090886 | 0.213056421 | | Serum cystatin C (eGFRcys) \|\| id:1106 | Weighted median | 5 | -0.15894753 | 0.251509163 | 0.527403144 | | Serum cystatin C (eGFRcys) \|\| id:1106 | Weighted mode | 5 | -0.207022133 | 0.266812702 | 0.481124282 | | Urinary albumin-to-creatinine ratio \|\| id:1107 | Wald ratio | 1 | 0.032786885 | 0.391803279 | 0.933309262 | | Ischemic stroke \|\| id:1108 | Wald ratio | 1 | -0.133681852 | 0.174757282 | 0.444296992 | | Cardioembolic stroke \|\| id:1109 | Wald ratio | 1 | -0.108735214 | 0.095086442 | 0.252814179 | | Large vessel disease \|\| id:1110 | Wald ratio | 1 | -0.011617242 | 0.064506267 | 0.857078155 | | Primary sclerosing cholangitis \|\| id:1112 | Inverse variance weighted | 14 | -0.040160471 | 0.023574575 | 0.088465159 | | Primary sclerosing cholangitis \|\| id:1112 | MR Egger | 14 | -0.012277761 | 0.042129694 | 0.775700478 | | Primary sclerosing cholangitis \|\| id:1112 | Weighted median | 14 | -0.020763178 | 0.021598409 | 0.336386731 | | Primary sclerosing cholangitis \|\| id:1112 | Weighted mode | 14 | -0.022110857 | 0.021213533 | 0.316269259 | | Adrenic acid (22:4n6) \|\| id:1138 | Wald ratio | 1 | 0.256198347 | 0.33677686 | 0.44681465 | | Gamma-linolenic acid (18:3n6) \|\| id:1139 | Inverse variance weighted | 167 | 0.012621011 | 0.0263069 | 0.631397729 | | Gamma-linolenic acid (18:3n6) \|\| id:1139 | MR Egger | 167 | -0.016472795 | 0.06370245 | 0.79627415 | | Gamma-linolenic acid (18:3n6) \|\| id:1139 | Weighted median | 167 | -0.005684929 | 0.036466372 | 0.876115703 | | Gamma-linolenic acid (18:3n6) \|\| id:1139 | Weighted mode | 167 | -0.009968272 | 0.034708794 | 0.774319441 | | Neo-conscientiousness \|\| id:114 | Wald ratio | 1 | 0.019136408 | 0.039499509 | 0.628050896 | | Dihomo-gamma-linolenic acid (20:3n6) \|\| id:1140 | Inverse variance weighted | 66 | 0.004896307 | 0.004199637 | 0.243659638 | | Dihomo-gamma-linolenic acid (20:3n6) \|\| id:1140 | MR Egger | 66 | 0.002658206 | 0.009914327 | 0.789471087 | | Dihomo-gamma-linolenic acid (20:3n6) \|\| id:1140 | Weighted median | 66 | -0.001870339 | 0.006062714 | 0.757702916 | | Dihomo-gamma-linolenic acid (20:3n6) \|\| id:1140 | Weighted mode | 66 | 0.001892989 | 0.005142875 | 0.714009688 | | Arachidonic acid (20:4n6) \|\| id:1141 | Inverse variance weighted | 56 | 0.002920382 | 0.002147511 | 0.173864166 | | Arachidonic acid (20:4n6) \|\| id:1141 | MR Egger | 56 | 0.002382345 | 0.003770811 | 0.530192516 | | Arachidonic acid (20:4n6) \|\| id:1141 | Weighted median | 56 | 0.001504894 | 0.003031919 | 0.619647336 | | Arachidonic acid (20:4n6) \|\| id:1141 | Weighted mode | 56 | 0.003180937 | 0.002572459 | 0.221513922 | | Linoleic acid (18:2n6) \|\| id:1142 | Inverse variance weighted | 71 | -0.001742599 | 0.000831897 | 0.03619506 | | Linoleic acid (18:2n6) \|\| id:1142 | MR Egger | 71 | -0.00256867 | 0.001280228 | 0.048732888 | | Linoleic acid (18:2n6) \|\| id:1142 | Weighted median | 71 | -0.001877782 | 0.001165946 | 0.10728384 | | Linoleic acid (18:2n6) \|\| id:1142 | Weighted mode | 71 | -0.00160685 | 0.000904134 | 0.079875292 | | Docosapentaenoic acid (22:5n3) \|\| id:1144 | Inverse variance weighted | 3 | 0.072327777 | 0.187915957 | 0.700315745 | | Docosapentaenoic acid (22:5n3) \|\| id:1144 | MR Egger | 3 | 0.270323923 | 0.393808459 | 0.617032574 | | Docosapentaenoic acid (22:5n3) \|\| id:1144 | Weighted median | 3 | 0.051117985 | 0.187961623 | 0.785653011 | | Docosapentaenoic acid (22:5n3) \|\| id:1144 | Weighted mode | 3 | 0.158085835 | 0.210432052 | 0.53087247 | | ?-linolenic acid (18:3n3) \|\| id:1145 | Wald ratio | 1 | -0.742138365 | 1.025157233 | 0.469110933 | | Eicosapentaenoic acid (20:5n3) \|\| id:1147 | Inverse variance weighted | 2 | 0.025574004 | 0.092292442 | 0.781705248 | | trans-cis-18:2 \|\| id:1148 | Wald ratio | 1 | 2.203931204 | 1.35995086 | 0.105104266 | | cis-trans-18:2 \|\| id:1150 | Inverse variance weighted | 2 | -2.011286554 | 2.576281994 | 0.434982797 | | Oleic acid (18:1n9) \|\| id:1155 | Wald ratio | 1 | -0.042608696 | 0.072608696 | 0.55732034 | | palmitoleic acid (16:1n7) \|\| id:1156 | Inverse variance weighted | 5 | 0.236729204 | 0.451608136 | 0.600145263 | | palmitoleic acid (16:1n7) \|\| id:1156 | MR Egger | 5 | -0.088906005 | 2.296072324 | 0.971545539 | | palmitoleic acid (16:1n7) \|\| id:1156 | Weighted median | 5 | 0.130037207 | 0.43690463 | 0.765983335 | | palmitoleic acid (16:1n7) \|\| id:1156 | Weighted mode | 5 | 0.517805975 | 0.648408657 | 0.469262614 | | Palmitic acid (16:0) plasma levels \|\| id:1157 | Wald ratio | 1 | -0.025352113 | 0.087887324 | 0.772993468 | | Stearic acid (18:0) plasma levels \|\| id:1158 | Inverse variance weighted | 2 | 0.039139007 | 0.067056215 | 0.559439283 | | Neo-openness to experience \|\| id:117 | Wald ratio | 1 | 0.019983347 | 0.039550375 | 0.613374016 | | Neuroticism \|\| id:118 | Wald ratio | 1 | 0.801488834 | 0.508684864 | 0.115115766 | | Crohn's disease \|\| id:12 | Inverse variance weighted | 109 | -0.028397255 | 0.017103721 | 0.096854737 | | Crohn's disease \|\| id:12 | MR Egger | 109 | 0.01052065 | 0.045896143 | 0.819129817 | | Crohn's disease \|\| id:12 | Weighted median | 109 | -0.023259193 | 0.021905598 | 0.288330036 | | Crohn's disease \|\| id:12 | Weighted mode | 109 | -0.019522404 | 0.026911672 | 0.469760201 | | Body mass index \|\| id:2 | Inverse variance weighted | 75 | -0.011364864 | 0.096246234 | 0.906003378 | | Body mass index \|\| id:2 | MR Egger | 75 | -0.202511926 | 0.230662491 | 0.382847131 | | Body mass index \|\| id:2 | Weighted median | 75 | 0.00625262 | 0.141268923 | 0.964696831 | | Body mass index \|\| id:2 | Weighted mode | 75 | 0.096205264 | 0.169062958 | 0.571045439 | | Schizophrenia \|\| id:22 | Inverse variance weighted | 68 | 0.026414399 | 0.033826454 | 0.434873117 | | Schizophrenia \|\| id:22 | MR Egger | 68 | 0.053268017 | 0.162452404 | 0.744025798 | | Schizophrenia \|\| id:22 | Weighted median | 68 | 0.034610706 | 0.041790667 | 0.407561636 | | Schizophrenia \|\| id:22 | Weighted mode | 68 | 0.038087434 | 0.100243737 | 0.705185588 | | Type 2 diabetes \|\| id:23 | Inverse variance weighted | 25 | 0.043398668 | 0.049519566 | 0.380815685 | | Type 2 diabetes \|\| id:23 | MR Egger | 25 | 0.140480224 | 0.193159884 | 0.47439642 | | Type 2 diabetes \|\| id:23 | Weighted median | 25 | 0.10574622 | 0.053487168 | 0.048037218 | | Type 2 diabetes \|\| id:23 | Weighted mode | 25 | 0.166960683 | 0.084308368 | 0.059238153 | | Type 2 diabetes \|\| id:24 | Inverse variance weighted | 35 | 0.024565978 | 0.036101688 | 0.49620932 | | Type 2 diabetes \|\| id:24 | MR Egger | 35 | -0.019723414 | 0.086336747 | 0.820708113 | | Type 2 diabetes \|\| id:24 | Weighted median | 35 | -0.013572523 | 0.043630717 | 0.755741912 | | Type 2 diabetes \|\| id:24 | Weighted mode | 35 | -0.007266328 | 0.044017217 | 0.869859243 | | Type 2 diabetes \|\| id:25 | Inverse variance weighted | 19 | 0.043105872 | 0.052948929 | 0.41558605 | | Type 2 diabetes \|\| id:25 | MR Egger | 19 | 0.141364875 | 0.184412427 | 0.453851954 | | Type 2 diabetes \|\| id:25 | Weighted median | 19 | 0.007128092 | 0.056703027 | 0.899962115 | | Type 2 diabetes \|\| id:25 | Weighted mode | 19 | -0.01590752 | 0.088349711 | 0.85912345 | | Type 2 diabetes \|\| id:26 | Inverse variance weighted | 10 | 0.026947366 | 0.054808886 | 0.622959343 | | Type 2 diabetes \|\| id:26 | MR Egger | 10 | -0.059848317 | 0.322672251 | 0.857471128 | | Type 2 diabetes \|\| id:26 | Weighted median | 10 | 0.029557358 | 0.057218038 | 0.60545348 | | Type 2 diabetes \|\| id:26 | Weighted mode | 10 | 0.015280103 | 0.087831757 | 0.865739186 | | Birth weight \|\| id:27 | Inverse variance weighted | 4 | -0.110474436 | 0.231559328 | 0.633298661 | | Birth weight \|\| id:27 | MR Egger | 4 | 0.047249964 | 1.562871245 | 0.97862707 | | Birth weight \|\| id:27 | Weighted median | 4 | -0.274464639 | 0.166859828 | 0.099994257 | | Birth weight \|\| id:27 | Weighted mode | 4 | -0.278007299 | 0.195105871 | 0.249403232 | | Haemoglobin concentration \|\| id:270 | Inverse variance weighted | 15 | -0.176232821 | 0.101444385 | 0.082345553 | | Haemoglobin concentration \|\| id:270 | MR Egger | 15 | -0.300969187 | 0.288935322 | 0.316559703 | | Haemoglobin concentration \|\| id:270 | Weighted median | 15 | -0.110999067 | 0.127694327 | 0.384707094 | | Haemoglobin concentration \|\| id:270 | Weighted mode | 15 | -0.181944722 | 0.164466886 | 0.287257565 | | Mean cell haemoglobin \|\| id:271 | Inverse variance weighted | 30 | 0.010479179 | 0.029757133 | 0.724720631 | | Mean cell haemoglobin \|\| id:271 | MR Egger | 30 | -0.008084721 | 0.064717918 | 0.901477524 | | Mean cell haemoglobin \|\| id:271 | Weighted median | 30 | -0.003214242 | 0.041807728 | 0.938717795 | | Mean cell haemoglobin \|\| id:271 | Weighted mode | 30 | -0.008997455 | 0.050117972 | 0.858773587 | | Mean cell haemoglobin concentration \|\| id:272 | Inverse variance weighted | 13 | -0.040276727 | 0.396806263 | 0.919151774 | | Mean cell haemoglobin concentration \|\| id:272 | MR Egger | 13 | -2.368614331 | 2.066934701 | 0.276132089 | | Mean cell haemoglobin concentration \|\| id:272 | Weighted median | 13 | -0.073137983 | 0.461572447 | 0.874099096 | | Mean cell haemoglobin concentration \|\| id:272 | Weighted mode | 13 | 0.080964313 | 0.652165565 | 0.9032543 | | Mean cell volume \|\| id:273 | Inverse variance weighted | 38 | 0.001575108 | 0.011612044 | 0.892102455 | | Mean cell volume \|\| id:273 | MR Egger | 38 | -0.005424905 | 0.027008744 | 0.841940619 | | Mean cell volume \|\| id:273 | Weighted median | 38 | 0.001793402 | 0.017471672 | 0.918243724 | | Mean cell volume \|\| id:273 | Weighted mode | 38 | -0.004387295 | 0.020844653 | 0.834451189 | | Packed cell volume \|\| id:274 | Inverse variance weighted | 12 | -0.045955362 | 0.035044091 | 0.189736715 | | Packed cell volume \|\| id:274 | MR Egger | 12 | 0.021040866 | 0.158354011 | 0.896930072 | | Packed cell volume \|\| id:274 | Weighted median | 12 | -0.02844461 | 0.048965097 | 0.561297044 | | Packed cell volume \|\| id:274 | Weighted mode | 12 | -0.021445712 | 0.076046221 | 0.783171789 | | Red blood cell count \|\| id:275 | Inverse variance weighted | 25 | -0.071718645 | 0.229714623 | 0.754882778 | | Red blood cell count \|\| id:275 | MR Egger | 25 | -0.19215006 | 0.620435896 | 0.759576344 | | Red blood cell count \|\| id:275 | Weighted median | 25 | -0.068769598 | 0.310726342 | 0.824844172 | | Red blood cell count \|\| id:275 | Weighted mode | 25 | -0.179512438 | 0.342928518 | 0.605448262 | | Celiac disease \|\| id:276 | Inverse variance weighted | 12 | -0.030398621 | 0.023744945 | 0.200469727 | | Celiac disease \|\| id:276 | MR Egger | 12 | -0.089404488 | 0.089964284 | 0.343768877 | | Celiac disease \|\| id:276 | Weighted median | 12 | -0.035975157 | 0.030646501 | 0.240445161 | | Celiac disease \|\| id:276 | Weighted mode | 12 | -0.034704332 | 0.043571156 | 0.442594119 | | Birth length \|\| id:29 | Inverse variance weighted | 2 | -0.221601646 | 0.291939746 | 0.44781285 | | Inflammatory bowel disease \|\| id:292 | Inverse variance weighted | 109 | -0.023164534 | 0.01980593 | 0.242171768 | | Inflammatory bowel disease \|\| id:292 | MR Egger | 109 | 0.000384328 | 0.046446197 | 0.993413228 | | Inflammatory bowel disease \|\| id:292 | Weighted median | 109 | -0.026198004 | 0.02458199 | 0.286541295 | | Inflammatory bowel disease \|\| id:292 | Weighted mode | 109 | -0.037687267 | 0.033128859 | 0.257806596 | | Inflammatory bowel disease \|\| id:293 | Inverse variance weighted | 7 | 0.001075582 | 0.019479556 | 0.955966417 | | Inflammatory bowel disease \|\| id:293 | MR Egger | 7 | 0.005593502 | 0.04982234 | 0.914978124 | | Inflammatory bowel disease \|\| id:293 | Weighted median | 7 | -0.033617919 | 0.021964107 | 0.125872153 | | Inflammatory bowel disease \|\| id:293 | Weighted mode | 7 | -0.032964442 | 0.024748125 | 0.231222031 | | Inflammatory bowel disease \|\| id:294 | Inverse variance weighted | 121 | -0.02239647 | 0.017953303 | 0.21221983 | | Inflammatory bowel disease \|\| id:294 | MR Egger | 121 | -0.012708459 | 0.043084837 | 0.768535656 | | Inflammatory bowel disease \|\| id:294 | Weighted median | 121 | -0.032105576 | 0.027484588 | 0.242754279 | | Inflammatory bowel disease \|\| id:294 | Weighted mode | 121 | -0.034883488 | 0.034579363 | 0.315102779 | | Inflammatory bowel disease \|\| id:295 | Wald ratio | 1 | 0.01622497 | 0.064751029 | 0.802142934 | | HDL cholesterol \|\| id:299 | Inverse variance weighted | 85 | -0.273582464 | 0.227666541 | 0.229487302 | | HDL cholesterol \|\| id:299 | MR Egger | 85 | -0.325494368 | 0.425936235 | 0.446923674 | | HDL cholesterol \|\| id:299 | Weighted median | 85 | 0.052013356 | 0.074736154 | 0.486454029 | | HDL cholesterol \|\| id:299 | Weighted mode | 85 | 0.029616797 | 0.070454717 | 0.675291215 | | Crohn's disease \|\| id:30 | Inverse variance weighted | 45 | -0.018439348 | 0.0174674 | 0.291131105 | | Crohn's disease \|\| id:30 | MR Egger | 45 | -0.012996719 | 0.040029091 | 0.746996224 | | Crohn's disease \|\| id:30 | Weighted median | 45 | -0.025923075 | 0.019355884 | 0.180477415 | | Crohn's disease \|\| id:30 | Weighted mode | 45 | -0.027217972 | 0.023073485 | 0.244489786 | | LDL cholesterol \|\| id:300 | Inverse variance weighted | 72 | 0.170160884 | 0.101757996 | 0.094482638 | | LDL cholesterol \|\| id:300 | MR Egger | 72 | 0.324701618 | 0.162870614 | 0.05009173 | | LDL cholesterol \|\| id:300 | Weighted median | 72 | 0.045134672 | 0.069176371 | 0.514105806 | | LDL cholesterol \|\| id:300 | Weighted mode | 72 | 0.066230559 | 0.075196402 | 0.381415353 | | Total cholesterol \|\| id:301 | Inverse variance weighted | 80 | 0.25351367 | 0.119631925 | 0.034080845 | | Total cholesterol \|\| id:301 | MR Egger | 80 | 0.510571152 | 0.205594414 | 0.015159248 | | Total cholesterol \|\| id:301 | Weighted median | 80 | 0.052971113 | 0.07328193 | 0.469778162 | | Total cholesterol \|\| id:301 | Weighted mode | 80 | 0.011182476 | 0.077872031 | 0.88618148 | | Triglycerides \|\| id:302 | Inverse variance weighted | 52 | 0.209699313 | 0.150283432 | 0.162907661 | | Triglycerides \|\| id:302 | MR Egger | 52 | 0.242648469 | 0.246633208 | 0.32992947 | | Triglycerides \|\| id:302 | Weighted median | 52 | 0.031888214 | 0.087563103 | 0.715728003 | | Triglycerides \|\| id:302 | Weighted mode | 52 | 0.034570793 | 0.080129986 | 0.667971233 | | Glutamine \|\| id:303 | Wald ratio | 1 | -3.113333333 | 1.38 | 0.024068211 | | Tryptophan \|\| id:304 | Inverse variance weighted | 17 | 0.139390245 | 0.962710509 | 0.884877178 | | Tryptophan \|\| id:304 | MR Egger | 17 | 7.52110863 | 12.95955189 | 0.570293292 | | Tryptophan \|\| id:304 | Weighted median | 17 | -0.539892398 | 1.064450713 | 0.61201252 | | Tryptophan \|\| id:304 | Weighted mode | 17 | -0.934873033 | 2.013915449 | 0.648753169 | | Leucine \|\| id:306 | Inverse variance weighted | 12 | 0.648163116 | 0.847079382 | 0.444167942 | | Leucine \|\| id:306 | MR Egger | 12 | 2.613512316 | 5.476421156 | 0.643456853 | | Leucine \|\| id:306 | Weighted median | 12 | 0.982303725 | 1.118575816 | 0.379849529 | | Leucine \|\| id:306 | Weighted mode | 12 | 1.310094682 | 1.502815174 | 0.40196595 | | Cholesterol \|\| id:307 | Inverse variance weighted | 2 | -0.471383049 | 1.026603533 | 0.646113837 | | Phenylalanine \|\| id:308 | Wald ratio | 1 | -0.32 | 2.093333333 | 0.878503758 | | Inflammatory bowel disease \|\| id:31 | Inverse variance weighted | 56 | -0.007741119 | 0.022657947 | 0.732613264 | | Inflammatory bowel disease \|\| id:31 | MR Egger | 56 | 0.035373888 | 0.061322811 | 0.56643979 | | Inflammatory bowel disease \|\| id:31 | Weighted median | 56 | -0.008106873 | 0.026799421 | 0.762269578 | | Inflammatory bowel disease \|\| id:31 | Weighted mode | 56 | -0.016616543 | 0.032915554 | 0.615699642 | | Mannose \|\| id:314 | Wald ratio | 1 | 0.018223235 | 0.366742597 | 0.960369871 | | Uridine \|\| id:316 | Inverse variance weighted | 3 | -0.559673039 | 1.057987687 | 0.596807055 | | Uridine \|\| id:316 | MR Egger | 3 | -7.868632785 | 4.608335361 | 0.337286173 | | Uridine \|\| id:316 | Weighted median | 3 | 0.248283194 | 1.141417895 | 0.827801775 | | Uridine \|\| id:316 | Weighted mode | 3 | 0.718198727 | 1.707440221 | 0.714913257 | | Ulcerative colitis \|\| id:32 | Inverse variance weighted | 33 | 0.031893663 | 0.026949332 | 0.236623849 | | Ulcerative colitis \|\| id:32 | MR Egger | 33 | 0.178190504 | 0.07258666 | 0.019905606 | | Ulcerative colitis \|\| id:32 | Weighted median | 33 | -0.004759503 | 0.027167161 | 0.860927792 | | Ulcerative colitis \|\| id:32 | Weighted mode | 33 | -0.02818191 | 0.041946074 | 0.50649453 | | Deoxycholate \|\| id:320 | Wald ratio | 1 | -0.136986301 | 0.457534247 | 0.764633948 | | Margarate (17:0) \|\| id:321 | Wald ratio | 1 | -1.126712329 | 0.688356164 | 0.101668938 | | Inosine \|\| id:322 | Wald ratio | 1 | 0.106598985 | 0.21319797 | 0.617075077 | | Tyrosine \|\| id:325 | Inverse variance weighted | 3 | -0.865204389 | 1.564044647 | 0.580137459 | | Tyrosine \|\| id:325 | MR Egger | 3 | -1.00020864 | 22.544358 | 0.971774077 | | Tyrosine \|\| id:325 | Weighted median | 3 | -0.703067906 | 1.249863978 | 0.573764821 | | Tyrosine \|\| id:325 | Weighted mode | 3 | -0.443553681 | 1.566227144 | 0.803646462 | | Lysine \|\| id:326 | Wald ratio | 1 | -0.300699301 | 1.188811189 | 0.80031367 | | Methionine \|\| id:327 | Wald ratio | 1 | -3.255319149 | 2.659574468 | 0.220952228 | | Malate \|\| id:328 | Wald ratio | 1 | -0.95 | 1.08125 | 0.379611298 | | Palmitate (16:0) \|\| id:329 | Wald ratio | 1 | -2.178807947 | 1.331125828 | 0.101668938 | | Nonadecanoate (19:0) \|\| id:330 | Wald ratio | 1 | -1.807692308 | 1.104395604 | 0.101668938 | | Stearate (18:0) \|\| id:331 | Inverse variance weighted | 2 | -1.16544658 | 0.76301855 | 0.126657653 | | Oleate (18:1n9) \|\| id:332 | Wald ratio | 1 | -0.290697674 | 1.168604651 | 0.803549359 | | Pentadecanoate (15:0) \|\| id:333 | Wald ratio | 1 | -0.542253521 | 1.302816901 | 0.677251795 | | Pipecolate \|\| id:335 | Wald ratio | 1 | 0.419047619 | 0.628571429 | 0.504985075 | | 5-oxoproline \|\| id:337 | Wald ratio | 1 | -0.822605965 | 0.519623234 | 0.113402873 | | Pantothenate \|\| id:338 | Wald ratio | 1 | -0.023255814 | 0.970930233 | 0.98089082 | | 4-acetamidobutanoate \|\| id:339 | Inverse variance weighted | 2 | 0.119222275 | 0.573717776 | 0.835380069 | | Citrate \|\| id:341 | Inverse variance weighted | 6 | -1.155588186 | 0.580810157 | 0.046633441 | | Citrate \|\| id:341 | MR Egger | 6 | -1.724516764 | 1.819295746 | 0.396853731 | | Citrate \|\| id:341 | Weighted median | 6 | -1.255677985 | 0.728167828 | 0.08462937 | | Citrate \|\| id:341 | Weighted mode | 6 | -1.620458173 | 0.966935489 | 0.154612473 | | N-acetylalanine \|\| id:344 | Wald ratio | 1 | 1.453608247 | 2.288659794 | 0.525340284 | | Heptanoate (7:0) \|\| id:349 | Inverse variance weighted | 2 | 0.370659572 | 1.106832751 | 0.737713278 | | Laurate (12:0) \|\| id:350 | Inverse variance weighted | 2 | 2.103196355 | 1.154750101 | 0.068554689 | | Valine \|\| id:351 | Wald ratio | 1 | 1.481481481 | 2.012345679 | 0.461611232 | | Cortisone \|\| id:354 | Wald ratio | 1 | -0.545454545 | 1.636363636 | 0.73888268 | | Proline \|\| id:355 | Inverse variance weighted | 2 | -0.698708775 | 0.377256697 | 0.064014643 | | Citrulline \|\| id:356 | Inverse variance weighted | 3 | 1.357489816 | 0.993770423 | 0.171939147 | | Citrulline \|\| id:356 | MR Egger | 3 | 75.49482108 | 55.4718844 | 0.403417811 | | Citrulline \|\| id:356 | Weighted median | 3 | 1.509221843 | 1.24205996 | 0.224329555 | | Citrulline \|\| id:356 | Weighted mode | 3 | 2.016476549 | 1.80753501 | 0.380660023 | | Biliverdin \|\| id:357 | Wald ratio | 1 | 0.058355438 | 0.149425287 | 0.696142795 | | Gamma-glutamylglutamine \|\| id:359 | Inverse variance weighted | 3 | -1.428605853 | 0.655467912 | 0.029293012 | | Gamma-glutamylglutamine \|\| id:359 | MR Egger | 3 | -4.015497821 | 2.239400392 | 0.323866031 | | Gamma-glutamylglutamine \|\| id:359 | Weighted median | 3 | -1.832535463 | 0.756070209 | 0.0153606 | | Gamma-glutamylglutamine \|\| id:359 | Weighted mode | 3 | -1.918569454 | 0.873608236 | 0.159240888 | | Gamma-glutamyltyrosine \|\| id:360 | Inverse variance weighted | 3 | 0.850439336 | 0.942393573 | 0.36683125 | | Gamma-glutamyltyrosine \|\| id:360 | MR Egger | 3 | 8.421932646 | 31.00500816 | 0.831148238 | | Gamma-glutamyltyrosine \|\| id:360 | Weighted median | 3 | 0.583537181 | 1.144864454 | 0.610261795 | | Gamma-glutamyltyrosine \|\| id:360 | Weighted mode | 3 | 0.453017239 | 1.400430008 | 0.777020884 | | Hypoxanthine \|\| id:361 | Wald ratio | 1 | 0.024752475 | 0.787128713 | 0.974913425 | | Betaine \|\| id:362 | Inverse variance weighted | 3 | -0.015268284 | 0.552341116 | 0.977947003 | | Betaine \|\| id:362 | MR Egger | 3 | 0.819190231 | 1.791194882 | 0.726926109 | | Betaine \|\| id:362 | Weighted median | 3 | -0.0167149 | 0.630568289 | 0.978852411 | | Betaine \|\| id:362 | Weighted mode | 3 | -0.045526998 | 0.815781222 | 0.960568579 | | Pelargonate (9:0) \|\| id:366 | Wald ratio | 1 | -0.91 | 1.71 | 0.594612592 | | X-03094 \|\| id:373 | Inverse variance weighted | 3 | -1.040881181 | 0.703048963 | 0.13873334 | | X-03094 \|\| id:373 | MR Egger | 3 | 0.056228175 | 4.378927541 | 0.991825852 | | X-03094 \|\| id:373 | Weighted median | 3 | -0.646348009 | 0.790735058 | 0.413699028 | | X-03094 \|\| id:373 | Weighted mode | 3 | -0.423195149 | 1.009944152 | 0.715910407 | | Kynurenine \|\| id:375 | Inverse variance weighted | 3 | -0.028801259 | 0.990325108 | 0.976798689 | | Kynurenine \|\| id:375 | MR Egger | 3 | -1.343605203 | 3.680829644 | 0.777183462 | | Kynurenine \|\| id:375 | Weighted median | 3 | -0.241110566 | 0.612914084 | 0.694035919 | | Kynurenine \|\| id:375 | Weighted mode | 3 | -0.284511997 | 0.673749587 | 0.713884711 | | Acetylphosphate \|\| id:378 | Inverse variance weighted | 2 | -0.865989121 | 1.376024055 | 0.529125471 | | Carnitine \|\| id:379 | Inverse variance weighted | 16 | -0.496393213 | 0.741724959 | 0.50334136 | | Carnitine \|\| id:379 | MR Egger | 16 | 2.16611898 | 1.142147042 | 0.078716019 | | Carnitine \|\| id:379 | Weighted median | 16 | 1.43917376 | 0.807768422 | 0.074803669 | | Carnitine \|\| id:379 | Weighted mode | 16 | 1.265179517 | 0.796305902 | 0.132954457 | | N-acetylornithine \|\| id:381 | Wald ratio | 1 | -0.134299517 | 0.088405797 | 0.128730863 | | N1-methyladenosine \|\| id:382 | Wald ratio | 1 | 0.208333333 | 2.569444444 | 0.935377471 | | 3-methyl-2-oxovalerate \|\| id:383 | Inverse variance weighted | 3 | 0.36784908 | 0.825955937 | 0.656058438 | | 3-methyl-2-oxovalerate \|\| id:383 | MR Egger | 3 | 3.472914915 | 5.551724674 | 0.644130142 | | 3-methyl-2-oxovalerate \|\| id:383 | Weighted median | 3 | 0.246714652 | 0.888694072 | 0.781308048 | | 3-methyl-2-oxovalerate \|\| id:383 | Weighted mode | 3 | 0.856263585 | 1.097416414 | 0.516923475 | | 3-phenylpropionate (hydrocinnamate) \|\| id:385 | Wald ratio | 1 | -0.204620462 | 0.597359736 | 0.731943466 | | X-04499--3,4-dihydroxybutyrate \|\| id:393 | Wald ratio | 1 | 0.778280543 | 0.92760181 | 0.401455623 | | X-18601 \|\| id:396 | Inverse variance weighted | 2 | -0.63499551 | 0.45540555 | 0.16321142 | | Indolelactate \|\| id:399 | Wald ratio | 1 | -1.094240838 | 0.895287958 | 0.221623602 | | Eicosapentaenoate (EPA; 20:5n3) \|\| id:402 | Wald ratio | 1 | 0.252808989 | 0.488764045 | 0.60498767 | | Estrone 3-sulfate \|\| id:403 | Wald ratio | 1 | -0.412094065 | 0.162747294 | 0.011337839 | | Docosahexaenoate (DHA; 22:6n3) \|\| id:409 | Wald ratio | 1 | 0.524324324 | 0.843243243 | 0.534076759 | | X-06246 \|\| id:412 | Wald ratio | 1 | 0.195454545 | 0.854545455 | 0.819083903 | | X-06307 \|\| id:414 | Wald ratio | 1 | 0.193236715 | 0.405797101 | 0.633938684 | | Myo-inositol \|\| id:417 | Inverse variance weighted | 2 | 3.542010231 | 1.229214569 | 0.003957582 | | Glucose \|\| id:418 | Wald ratio | 1 | 1.565656566 | 1.747474747 | 0.370277461 | | 1,5-anhydroglucitol (1,5-AG) \|\| id:419 | Inverse variance weighted | 3 | -0.363916981 | 0.424453278 | 0.391235911 | | 1,5-anhydroglucitol (1,5-AG) \|\| id:419 | MR Egger | 3 | -1.996306748 | 1.112993535 | 0.323786852 | | 1,5-anhydroglucitol (1,5-AG) \|\| id:419 | Weighted median | 3 | -0.456275068 | 0.404893055 | 0.259783631 | | 1,5-anhydroglucitol (1,5-AG) \|\| id:419 | Weighted mode | 3 | -0.591027542 | 0.419341424 | 0.294095049 | | 3-methyl-2-oxobutyrate \|\| id:421 | Wald ratio | 1 | 0.983606557 | 1.336065574 | 0.461611232 | | 1,6-anhydroglucose \|\| id:422 | Wald ratio | 1 | 0.084710744 | 0.41322314 | 0.837572125 | | X-08402 \|\| id:426 | Inverse variance weighted | 2 | 0.307928297 | 0.291290227 | 0.290457495 | | 2-hydroxyisobutyrate \|\| id:427 | Inverse variance weighted | 3 | -0.559630799 | 0.506720716 | 0.269412439 | | 2-hydroxyisobutyrate \|\| id:427 | MR Egger | 3 | -1.560885239 | 1.259263229 | 0.432169754 | | 2-hydroxyisobutyrate \|\| id:427 | Weighted median | 3 | -0.65594773 | 0.554559826 | 0.23687815 | | 2-hydroxyisobutyrate \|\| id:427 | Weighted mode | 3 | -0.795967235 | 0.622426509 | 0.329292432 | | 4-methyl-2-oxopentanoate \|\| id:429 | Inverse variance weighted | 2 | 0.77082513 | 0.911325112 | 0.397648193 | | Phenyllactate (PLA) \|\| id:430 | Wald ratio | 1 | -0.255014327 | 0.76504298 | 0.73888268 | | Homocitrulline \|\| id:431 | Wald ratio | 1 | 0.24 | 0.501538462 | 0.63227473 | | Aspartylphenylalanine \|\| id:432 | Wald ratio | 1 | -1.008791209 | 0.340659341 | 0.00306353 | | Levulinate (4-oxovalerate) \|\| id:433 | Inverse variance weighted | 2 | -1.478223222 | 1.005332886 | 0.141458366 | | X-08988 \|\| id:435 | Inverse variance weighted | 2 | -0.619066325 | 0.544735223 | 0.255766759 | | Asthma \|\| id:44 | Inverse variance weighted | 7 | 0.009688281 | 0.043815427 | 0.825002314 | | Asthma \|\| id:44 | MR Egger | 7 | -0.117185979 | 0.267959473 | 0.68011804 | | Asthma \|\| id:44 | Weighted median | 7 | 0.002145557 | 0.057350899 | 0.970157268 | | Asthma \|\| id:44 | Weighted mode | 7 | -0.062219147 | 0.089287464 | 0.511982856 | | X-10395 \|\| id:440 | Wald ratio | 1 | -0.852760736 | 0.975460123 | 0.382001812 | | X-10429 \|\| id:441 | Wald ratio | 1 | -0.858024691 | 0.981481481 | 0.382001812 | | X-10510 \|\| id:444 | Inverse variance weighted | 3 | 0.439663233 | 0.419461112 | 0.294563936 | | X-10510 \|\| id:444 | MR Egger | 3 | -0.300281304 | 0.928337268 | 0.800840068 | | X-10510 \|\| id:444 | Weighted median | 3 | 0.412056015 | 0.446834955 | 0.35644198 | | X-10510 \|\| id:444 | Weighted mode | 3 | 0.242051577 | 0.476929126 | 0.662220939 | | 1-linoleoylglycerol (1-monolinolein) \|\| id:445 | Wald ratio | 1 | -0.038107753 | 0.399474376 | 0.924001296 | | Indoleacetate \|\| id:446 | Wald ratio | 1 | -0.006557377 | 1.163934426 | 0.995504899 | | N-acetylglycine \|\| id:449 | Inverse variance weighted | 2 | -0.094001118 | 0.278219367 | 0.735463484 | | Anorexia nervosa \|\| id:45 | Wald ratio | 1 | -0.000940645 | 0.008069745 | 0.907205236 | | Bilirubin (Z,Z) \|\| id:450 | Wald ratio | 1 | 0.039355993 | 0.100775194 | 0.696142795 | | Creatine \|\| id:451 | Wald ratio | 1 | -0.374722838 | 0.423503326 | 0.376255472 | | N-(2-furoyl)glycine \|\| id:457 | Wald ratio | 1 | 0.106778644 | 0.217156569 | 0.622922454 | | Androsterone sulfate \|\| id:460 | Inverse variance weighted | 3 | -0.167654417 | 0.102864863 | 0.103132957 | | Androsterone sulfate \|\| id:460 | MR Egger | 3 | -0.19344517 | 0.193936938 | 0.500808166 | | Androsterone sulfate \|\| id:460 | Weighted median | 3 | -0.186808209 | 0.098123734 | 0.056935912 | | Androsterone sulfate \|\| id:460 | Weighted mode | 3 | -0.191646548 | 0.10102549 | 0.198269828 | | 3-carboxy-4-methyl-5-propyl-2-furanpropanoate (CMPF) \|\| id:461 | Wald ratio | 1 | -0.284836066 | 0.319672131 | 0.372915415 | | 3-(4-hydroxyphenyl)lactate \|\| id:462 | Wald ratio | 1 | -0.128342246 | 0.957219251 | 0.893340728 | | Acetylcarnitine \|\| id:463 | Inverse variance weighted | 2 | -0.361676056 | 0.664442756 | 0.586214478 | | Serine \|\| id:464 | Inverse variance weighted | 3 | 0.154789831 | 0.520277029 | 0.766073928 | | Serine \|\| id:464 | MR Egger | 3 | -7.287861173 | 6.004683136 | 0.438734594 | | Serine \|\| id:464 | Weighted median | 3 | 0.265659433 | 0.647752598 | 0.681714369 | | Serine \|\| id:464 | Weighted mode | 3 | 0.542490546 | 0.847665925 | 0.587715412 | | Hexanoylcarnitine \|\| id:467 | Inverse variance weighted | 3 | 0.120559426 | 0.323600291 | 0.709478475 | | Hexanoylcarnitine \|\| id:467 | MR Egger | 3 | 0.769594331 | 0.541221979 | 0.390189343 | | Hexanoylcarnitine \|\| id:467 | Weighted median | 3 | 0.258276249 | 0.234675605 | 0.271085112 | | Hexanoylcarnitine \|\| id:467 | Weighted mode | 3 | 0.277619583 | 0.232904298 | 0.355524799 | | Glycine \|\| id:468 | Wald ratio | 1 | -0.222368421 | 0.251315789 | 0.376255472 | | Alanine \|\| id:469 | Inverse variance weighted | 2 | -0.987516793 | 1.230723284 | 0.422328929 | | Glycochenodeoxycholate \|\| id:470 | Wald ratio | 1 | 0.038506418 | 0.360560093 | 0.914950728 | | 2-aminobutyrate \|\| id:471 | Inverse variance weighted | 2 | 0.211768403 | 0.771221232 | 0.78363248 | | Dodecanedioate \|\| id:473 | Wald ratio | 1 | 0.586111111 | 0.705555556 | 0.406138232 | | Gamma-glutamylvaline \|\| id:474 | Wald ratio | 1 | -1.158273381 | 1.374100719 | 0.399266511 | | Indolepropionate \|\| id:475 | Wald ratio | 1 | -0.008474576 | 0.632768362 | 0.989314366 | | Butyrylcarnitine \|\| id:476 | Inverse variance weighted | 5 | 0.022637844 | 0.095558664 | 0.812734396 | | Butyrylcarnitine \|\| id:476 | MR Egger | 5 | 0.081569266 | 0.152471017 | 0.629775211 | | Butyrylcarnitine \|\| id:476 | Weighted median | 5 | 0.0351444 | 0.096760391 | 0.716447566 | | Butyrylcarnitine \|\| id:476 | Weighted mode | 5 | 0.035962033 | 0.102221652 | 0.742736081 | | Myristoleate (14:1n5) \|\| id:477 | Wald ratio | 1 | 0.894021739 | 0.546195652 | 0.101668938 | | Dehydroisoandrosterone sulfate (DHEA-S) \|\| id:478 | Inverse variance weighted | 2 | -0.614087946 | 0.443886574 | 0.166531716 | | Propionylcarnitine \|\| id:479 | Inverse variance weighted | 3 | 0.459178308 | 0.840066472 | 0.584655226 | | Propionylcarnitine \|\| id:479 | MR Egger | 3 | 2.765966036 | 1.157467651 | 0.25230821 | | Propionylcarnitine \|\| id:479 | Weighted median | 3 | 0.368113907 | 0.570866655 | 0.519035131 | | Propionylcarnitine \|\| id:479 | Weighted mode | 3 | 1.319756103 | 0.646100506 | 0.177821452 | | Hip circumference \|\| id:48 | Inverse variance weighted | 47 | -0.225407422 | 0.116394744 | 0.052797033 | | Hip circumference \|\| id:48 | MR Egger | 47 | -0.235398727 | 0.433749718 | 0.590009968 | | Hip circumference \|\| id:48 | Weighted median | 47 | -0.14429037 | 0.144429023 | 0.317775319 | | Hip circumference \|\| id:48 | Weighted mode | 47 | -0.620895603 | 0.265587692 | 0.023801552 | | Caprylate (8:0) \|\| id:481 | Inverse variance weighted | 2 | -1.451649277 | 1.168250956 | 0.21402138 | | 10-undecenoate (11:1n1) \|\| id:482 | Inverse variance weighted | 2 | -0.522563126 | 0.346868304 | 0.13193441 | | Docosapentaenoate (n3 DPA; 22:5n3) \|\| id:483 | Wald ratio | 1 | 0.424242424 | 0.636363636 | 0.504985075 | | X-11204 \|\| id:484 | Inverse variance weighted | 2 | -1.826738144 | 1.214275857 | 0.132482315 | | X-02269 \|\| id:485 | Inverse variance weighted | 2 | 0.022496373 | 0.253843118 | 0.92938142 | | X-11247 \|\| id:489 | Wald ratio | 1 | 0.320737327 | 0.283870968 | 0.258530952 | | Hip circumference \|\| id:49 | Inverse variance weighted | 52 | -0.182739834 | 0.106499567 | 0.086185115 | | Hip circumference \|\| id:49 | MR Egger | 52 | -0.195212042 | 0.324674803 | 0.550387113 | | Hip circumference \|\| id:49 | Weighted median | 52 | -0.074635071 | 0.136298833 | 0.583977521 | | Hip circumference \|\| id:49 | Weighted mode | 52 | -0.033026713 | 0.209049229 | 0.875092235 | | X-11261 \|\| id:490 | Wald ratio | 1 | 0.085106383 | 0.453900709 | 0.851268624 | | Bilirubin (E,E)\* \|\| id:491 | Wald ratio | 1 | 0.0515625 | 0.13203125 | 0.696142795 | | X-02249 \|\| id:492 | Wald ratio | 1 | -0.063122924 | 0.588039867 | 0.914515577 | | X-11315 \|\| id:495 | Inverse variance weighted | 3 | 0.217245528 | 0.451492224 | 0.630394083 | | X-11315 \|\| id:495 | MR Egger | 3 | 0.305824064 | 1.500298726 | 0.871983941 | | X-11315 \|\| id:495 | Weighted median | 3 | 0.212110692 | 0.503994199 | 0.67385776 | | X-11315 \|\| id:495 | Weighted mode | 3 | 0.199623724 | 0.610685626 | 0.774795387 | | X-11317 \|\| id:496 | Wald ratio | 1 | 0.44 | 1.055 | 0.676633343 | | 1-linoleoylglycerophosphoethanolamine\* \|\| id:497 | Inverse variance weighted | 2 | -0.300314682 | 0.341215891 | 0.378788349 | | X-11327 \|\| id:498 | Inverse variance weighted | 2 | 1.697183707 | 1.188802165 | 0.153394975 | | X-11334 \|\| id:499 | Wald ratio | 1 | 0.378109453 | 0.965174129 | 0.695241038 | | 3-dehydrocarnitine\* \|\| id:500 | Inverse variance weighted | 3 | -0.715620605 | 0.489131534 | 0.143455535 | | 3-dehydrocarnitine\* \|\| id:500 | MR Egger | 3 | -1.979352059 | 2.613288058 | 0.587322752 | | 3-dehydrocarnitine\* \|\| id:500 | Weighted median | 3 | -0.812013994 | 0.538151674 | 0.131325797 | | 3-dehydrocarnitine\* \|\| id:500 | Weighted mode | 3 | -0.843843826 | 0.571776914 | 0.277982303 | | Pyroglutamine\* \|\| id:501 | Inverse variance weighted | 3 | 0.210762148 | 0.270103906 | 0.435214161 | | Pyroglutamine\* \|\| id:501 | MR Egger | 3 | -1.143609854 | 1.348679576 | 0.552264398 | | Pyroglutamine\* \|\| id:501 | Weighted median | 3 | 0.308372901 | 0.319300171 | 0.334155561 | | Pyroglutamine\* \|\| id:501 | Weighted mode | 3 | 0.404550411 | 0.398654982 | 0.416999661 | | C-glycosyltryptophan\* \|\| id:502 | Wald ratio | 1 | 0.782733813 | 1.034532374 | 0.449285707 | | X-11381 \|\| id:504 | Wald ratio | 1 | 1.834745763 | 0.88559322 | 0.038286864 | | X-03056--N-\[3-(2-Oxopyrrolidin-1-yl)propyl]acetamide \|\| id:505 | Wald ratio | 1 | 0.425287356 | 0.750957854 | 0.571171828 | | X-11412 \|\| id:506 | Wald ratio | 1 | 0.283185841 | 1.460176991 | 0.846223337 | | X-01911 \|\| id:507 | Wald ratio | 1 | 0.080275229 | 0.360091743 | 0.823590037 | | X-11423--O-sulfo-L-tyrosine \|\| id:509 | Inverse variance weighted | 2 | -0.332182349 | 0.809982315 | 0.681724803 | | X-09789 \|\| id:510 | Wald ratio | 1 | -0.269633508 | 0.47382199 | 0.569314898 | | X-11440 \|\| id:513 | Inverse variance weighted | 3 | -0.015945617 | 0.224484203 | 0.943372092 | | X-11440 \|\| id:513 | MR Egger | 3 | 0.106826287 | 0.465572444 | 0.856412087 | | X-11440 \|\| id:513 | Weighted median | 3 | -0.020087956 | 0.129234213 | 0.876475736 | | X-11440 \|\| id:513 | Weighted mode | 3 | -0.016942202 | 0.13572698 | 0.912076796 | | X-11441 \|\| id:514 | Wald ratio | 1 | 0.098991751 | 0.153987168 | 0.520316801 | | X-11442 \|\| id:515 | Wald ratio | 1 | 0.099082569 | 0.15412844 | 0.520316801 | | X-11444 \|\| id:516 | Wald ratio | 1 | 0.574695122 | 0.567073171 | 0.310849631 | | X-11445--5-alpha-pregnan-3beta,20alpha-disulfate \|\| id:517 | Inverse variance weighted | 4 | 0.045862801 | 0.15505864 | 0.767400282 | | X-11445--5-alpha-pregnan-3beta,20alpha-disulfate \|\| id:517 | MR Egger | 4 | 0.826971206 | 1.021683926 | 0.503260787 | | X-11445--5-alpha-pregnan-3beta,20alpha-disulfate \|\| id:517 | Weighted median | 4 | 0.042625599 | 0.187343729 | 0.820014631 | | X-11445--5-alpha-pregnan-3beta,20alpha-disulfate \|\| id:517 | Weighted mode | 4 | 0.048313445 | 0.25737807 | 0.863079735 | | X-11452 \|\| id:518 | Wald ratio | 1 | 0.08259587 | 0.486725664 | 0.865248457 | | X-11469 \|\| id:519 | Inverse variance weighted | 3 | -0.171219544 | 0.224505507 | 0.445671044 | | X-11469 \|\| id:519 | MR Egger | 3 | 2.944353779 | 2.741757279 | 0.477326788 | | X-11469 \|\| id:519 | Weighted median | 3 | -0.21752719 | 0.275339147 | 0.429508119 | | X-11469 \|\| id:519 | Weighted mode | 3 | -0.366202289 | 0.343303305 | 0.397819377 | | X-11478 \|\| id:521 | Wald ratio | 1 | -0.002427184 | 0.430825243 | 0.995504899 | | X-11483 \|\| id:522 | Wald ratio | 1 | -0.181708785 | 0.427196149 | 0.67058001 | | X-11491 \|\| id:524 | Inverse variance weighted | 3 | 0.070633025 | 0.248221776 | 0.775984233 | | X-11491 \|\| id:524 | MR Egger | 3 | 0.485571233 | 0.991470616 | 0.710075197 | | X-11491 \|\| id:524 | Weighted median | 3 | 0.164723424 | 0.222562119 | 0.459225144 | | X-11491 \|\| id:524 | Weighted mode | 3 | 0.202521276 | 0.252696295 | 0.506962409 | | HWESASXX\* \|\| id:526 | Inverse variance weighted | 2 | 0.75867659 | 0.276537321 | 0.006079042 | | X-11521 \|\| id:527 | Wald ratio | 1 | -0.464454976 | 0.829383886 | 0.575479438 | | X-11529 \|\| id:528 | Inverse variance weighted | 2 | -0.00109141 | 0.157065113 | 0.994455725 | | X-11530 \|\| id:529 | Wald ratio | 1 | 0.059139785 | 0.151433692 | 0.696142795 | | X-11538 \|\| id:531 | Inverse variance weighted | 3 | 0.138831256 | 0.159427615 | 0.38385758 | | X-11538 \|\| id:531 | MR Egger | 3 | 0.203071412 | 0.317118271 | 0.63739919 | | X-11538 \|\| id:531 | Weighted median | 3 | 0.142004476 | 0.157765229 | 0.368067059 | | X-11538 \|\| id:531 | Weighted mode | 3 | 0.150976871 | 0.167738348 | 0.463073732 | | X-11550 \|\| id:534 | Wald ratio | 1 | 0.15625 | 1.770833333 | 0.929689666 | | X-11593--O-methylascorbate\* \|\| id:536 | Inverse variance weighted | 6 | 0.106007842 | 0.291606527 | 0.716208698 | | X-11593--O-methylascorbate\* \|\| id:536 | MR Egger | 6 | 0.048912844 | 0.47409744 | 0.922793275 | | X-11593--O-methylascorbate\* \|\| id:536 | Weighted median | 6 | 0.067673747 | 0.308571963 | 0.826406479 | | X-11593--O-methylascorbate\* \|\| id:536 | Weighted mode | 6 | 0.068729641 | 0.322883998 | 0.839841275 | | Adrenate (22:4n6) \|\| id:537 | Wald ratio | 1 | 0.357348703 | 0.469740634 | 0.44681465 | | ADSGEGDFXAEGGGVR\* \|\| id:539 | Inverse variance weighted | 2 | -0.01908531 | 0.165734689 | 0.908321638 | | Hip circumference \|\| id:54 | Inverse variance weighted | 68 | -0.225326736 | 0.085593619 | 0.008475455 | | Hip circumference \|\| id:54 | MR Egger | 68 | 0.135626632 | 0.337884758 | 0.689423055 | | Hip circumference \|\| id:54 | Weighted median | 68 | -0.105361332 | 0.116058825 | 0.363969648 | | Hip circumference \|\| id:54 | Weighted mode | 68 | 0.081905064 | 0.241284487 | 0.735329256 | | X-11787 \|\| id:541 | Inverse variance weighted | 2 | -0.517681454 | 0.387882766 | 0.181996226 | | X-11792 \|\| id:542 | Inverse variance weighted | 3 | -0.095035976 | 0.107703718 | 0.377569496 | | X-11792 \|\| id:542 | MR Egger | 3 | 0.004441803 | 0.443615543 | 0.993625911 | | X-11792 \|\| id:542 | Weighted median | 3 | -0.092639661 | 0.120377285 | 0.441550503 | | X-11792 \|\| id:542 | Weighted mode | 3 | -0.096030794 | 0.159676254 | 0.608656215 | | X-11793--oxidized bilirubin\* \|\| id:543 | Inverse variance weighted | 2 | 0.079422566 | 0.173400989 | 0.646932083 | | X-11799 \|\| id:545 | Wald ratio | 1 | 0.190026954 | 0.143530997 | 0.185521756 | | X-11820 \|\| id:548 | Wald ratio | 1 | 10.61470588 | 0.564705882 | 8.01E-79 | | Hip circumference \|\| id:55 | Inverse variance weighted | 68 | -0.213754307 | 0.087737736 | 0.014838905 | | Hip circumference \|\| id:55 | MR Egger | 68 | 0.038692423 | 0.331994664 | 0.907574286 | | Hip circumference \|\| id:55 | Weighted median | 68 | -0.116130584 | 0.113780544 | 0.307418329 | | Hip circumference \|\| id:55 | Weighted mode | 68 | 0.08414804 | 0.263206463 | 0.750187856 | | X-11858 \|\| id:555 | Wald ratio | 1 | -0.006169031 | 0.249845774 | 0.980301148 | | 1-arachidonoylglycerophosphocholine\* \|\| id:558 | Inverse variance weighted | 3 | 0.134844664 | 0.278753565 | 0.628569346 | | 1-arachidonoylglycerophosphocholine\* \|\| id:558 | MR Egger | 3 | 0.668682693 | 0.540978546 | 0.433039963 | | 1-arachidonoylglycerophosphocholine\* \|\| id:558 | Weighted median | 3 | 0.163720214 | 0.28974114 | 0.572035102 | | 1-arachidonoylglycerophosphocholine\* \|\| id:558 | Weighted mode | 3 | 0.257454572 | 0.305705008 | 0.488348871 | | 1-palmitoleoylglycerophosphocholine\* \|\| id:559 | Wald ratio | 1 | 1.200729927 | 0.733576642 | 0.101668938 | | X-11905 \|\| id:560 | Inverse variance weighted | 2 | 0.00629833 | 0.397345672 | 0.987353255 | | X-12013 \|\| id:562 | Wald ratio | 1 | -0.125757916 | 0.141477656 | 0.374062797 | | X-12038 \|\| id:566 | Wald ratio | 1 | 0.1171875 | 1.328125 | 0.929689666 | | X-12063 \|\| id:570 | Inverse variance weighted | 7 | -0.105158287 | 0.177974564 | 0.554613341 | | X-12063 \|\| id:570 | MR Egger | 7 | 0.084708505 | 0.281908216 | 0.775901791 | | X-12063 \|\| id:570 | Weighted median | 7 | -0.023865211 | 0.111576245 | 0.830631665 | | X-12063 \|\| id:570 | Weighted mode | 7 | -0.012974749 | 0.120747728 | 0.917932341 | | Gamma-glutamylphenylalanine \|\| id:572 | Inverse variance weighted | 2 | 0.526257986 | 1.41756144 | 0.710457482 | | Isobutyrylcarnitine \|\| id:573 | Inverse variance weighted | 2 | -0.72382955 | 0.435562092 | 0.096547142 | | Palmitoleate (16:1n7) \|\| id:576 | Wald ratio | 1 | 0.896457766 | 0.547683924 | 0.101668938 | | Erythronate\* \|\| id:578 | Inverse variance weighted | 3 | 0.154489818 | 1.608298463 | 0.923474565 | | Erythronate\* \|\| id:578 | MR Egger | 3 | 13.10347361 | 11.69696801 | 0.463934064 | | Erythronate\* \|\| id:578 | Weighted median | 3 | -0.982141095 | 1.10769334 | 0.375265034 | | Erythronate\* \|\| id:578 | Weighted mode | 3 | -1.207449738 | 1.159445882 | 0.40704074 | | X-12092 \|\| id:580 | Inverse variance weighted | 4 | -0.02590546 | 0.099003686 | 0.793582372 | | X-12092 \|\| id:580 | MR Egger | 4 | -0.029401319 | 0.162116643 | 0.872801453 | | X-12092 \|\| id:580 | Weighted median | 4 | -0.022569615 | 0.067267785 | 0.737233674 | | X-12092 \|\| id:580 | Weighted mode | 4 | -0.029306676 | 0.063003441 | 0.673501362 | | X-12093 \|\| id:581 | Wald ratio | 1 | 0.254882813 | 0.185546875 | 0.169539741 | | X-12094 \|\| id:582 | Wald ratio | 1 | -1.799019608 | 0.784313725 | 0.021804863 | | X-12095--N1-methyl-3-pyridone-4-carboxamide \|\| id:583 | Wald ratio | 1 | -2.027624309 | 0.883977901 | 0.021804863 | | X-12100--hydroxytryptophan\* \|\| id:584 | Wald ratio | 1 | 0.170886076 | 1.107594937 | 0.877384461 | | X-12188 \|\| id:587 | Inverse variance weighted | 2 | 0.005835489 | 0.097407865 | 0.952229084 | | X-12189 \|\| id:588 | Inverse variance weighted | 2 | 0.033535285 | 0.082322107 | 0.683738679 | | X-12244--N-acetylcarnosine \|\| id:596 | Inverse variance weighted | 3 | -0.097139276 | 0.60524573 | 0.872490688 | | X-12244--N-acetylcarnosine \|\| id:596 | MR Egger | 3 | 1.925693663 | 9.037522518 | 0.866349332 | | X-12244--N-acetylcarnosine \|\| id:596 | Weighted median | 3 | 0.019024746 | 0.562696511 | 0.973028695 | | X-12244--N-acetylcarnosine \|\| id:596 | Weighted mode | 3 | 0.328820929 | 0.815973793 | 0.725958738 | | Coronary heart disease \|\| id:6 | Inverse variance weighted | 3 | 0.054657325 | 0.059149103 | 0.355455041 | | Coronary heart disease \|\| id:6 | MR Egger | 3 | 0.355252715 | 0.516695811 | 0.6165516 | | Coronary heart disease \|\| id:6 | Weighted median | 3 | 0.070094184 | 0.066313256 | 0.29050421 | | Coronary heart disease \|\| id:6 | Weighted mode | 3 | 0.106605839 | 0.079811818 | 0.313357768 | | Waist circumference \|\| id:60 | Inverse variance weighted | 44 | -0.054430702 | 0.129070715 | 0.673235061 | | Waist circumference \|\| id:60 | MR Egger | 44 | -0.065733923 | 0.352859454 | 0.853114818 | | Waist circumference \|\| id:60 | Weighted median | 44 | 0.003140324 | 0.163967779 | 0.984719785 | | Waist circumference \|\| id:60 | Weighted mode | 44 | 0.051262749 | 0.198002251 | 0.796947909 | | ADpSGEGDFXAEGGGVR\* \|\| id:601 | Inverse variance weighted | 2 | 0.199673486 | 0.292658033 | 0.49506459 | | 1-eicosatrienoylglycerophosphocholine\* \|\| id:602 | Inverse variance weighted | 2 | -0.629025322 | 0.455757914 | 0.16753301 | | 1-eicosadienoylglycerophosphocholine\* \|\| id:607 | Wald ratio | 1 | -0.566502463 | 0.802955665 | 0.480485774 | | X-12435 \|\| id:608 | Wald ratio | 1 | 0.098480334 | 0.115315852 | 0.393102126 | | Waist circumference \|\| id:61 | Inverse variance weighted | 39 | -0.052397904 | 0.146339593 | 0.720300717 | | Waist circumference \|\| id:61 | MR Egger | 39 | -0.589681786 | 0.507328406 | 0.252545054 | | Waist circumference \|\| id:61 | Weighted median | 39 | 0.079366786 | 0.167400627 | 0.635419445 | | Waist circumference \|\| id:61 | Weighted mode | 39 | -0.347596986 | 0.370170984 | 0.35365253 | | X-12442--5,8-tetradecadienoate \|\| id:610 | Wald ratio | 1 | 0.476851852 | 0.365740741 | 0.192302646 | | X-12456 \|\| id:613 | Inverse variance weighted | 2 | 0.063654998 | 0.239030294 | 0.790004207 | | Octanoylcarnitine \|\| id:615 | Inverse variance weighted | 2 | 0.239664898 | 0.195412613 | 0.220027267 | | Alpha-hydroxyisovalerate \|\| id:616 | Inverse variance weighted | 3 | -0.570312902 | 0.349458981 | 0.102681991 | | Alpha-hydroxyisovalerate \|\| id:616 | MR Egger | 3 | -2.005689146 | 1.041634508 | 0.304940612 | | Alpha-hydroxyisovalerate \|\| id:616 | Weighted median | 3 | -0.464435096 | 0.348614019 | 0.18278364 | | Alpha-hydroxyisovalerate \|\| id:616 | Weighted mode | 3 | -0.968827754 | 0.390959209 | 0.131480479 | | Decanoylcarnitine \|\| id:618 | Inverse variance weighted | 3 | 0.279918061 | 0.213495441 | 0.189817354 | | Decanoylcarnitine \|\| id:618 | MR Egger | 3 | -0.018157887 | 0.615102622 | 0.981212381 | | Decanoylcarnitine \|\| id:618 | Weighted median | 3 | 0.281586162 | 0.237902332 | 0.236563181 | | Decanoylcarnitine \|\| id:618 | Weighted mode | 3 | 0.34064114 | 0.301502801 | 0.375830595 | | 5-dodecenoate (12:1n7) \|\| id:623 | Wald ratio | 1 | 1.068181818 | 0.652597403 | 0.101668938 | | Stearidonate (18:4n3) \|\| id:624 | Wald ratio | 1 | 0.139880952 | 0.511904762 | 0.784656579 | | 10-nonadecenoate (19:1n9) \|\| id:626 | Wald ratio | 1 | -0.215517241 | 0.86637931 | 0.803549359 | | Epiandrosterone sulfate \|\| id:627 | Inverse variance weighted | 2 | -0.410032612 | 0.201898025 | 0.042266188 | | X-12510--2-aminooctanoic acid \|\| id:629 | Inverse variance weighted | 3 | -0.203276419 | 0.170260468 | 0.232511469 | | X-12510--2-aminooctanoic acid \|\| id:629 | MR Egger | 3 | -0.272327045 | 0.387797636 | 0.610243681 | | X-12510--2-aminooctanoic acid \|\| id:629 | Weighted median | 3 | -0.246340143 | 0.155068201 | 0.112152479 | | X-12510--2-aminooctanoic acid \|\| id:629 | Weighted mode | 3 | -0.246362907 | 0.161576851 | 0.266818753 | | X-12524 \|\| id:630 | Inverse variance weighted | 2 | 0.294618517 | 1.403402369 | 0.833721052 | | Bilirubin (E,Z or Z,E)\* \|\| id:631 | Wald ratio | 1 | 0.081481481 | 0.208641975 | 0.696142795 | | X-12556 \|\| id:633 | Inverse variance weighted | 2 | -0.224452434 | 0.610424061 | 0.713097543 | | 1-arachidonoylglycerophosphoinositol\* \|\| id:634 | Inverse variance weighted | 2 | 0.270691888 | 0.432140523 | 0.53105403 | | X-12644 \|\| id:636 | Inverse variance weighted | 3 | -0.474089902 | 0.966930772 | 0.623918887 | | X-12644 \|\| id:636 | MR Egger | 3 | 9.018519365 | 4.001724645 | 0.265866258 | | X-12644 \|\| id:636 | Weighted median | 3 | 0.110976488 | 0.782174783 | 0.887173247 | | X-12644 \|\| id:636 | Weighted mode | 3 | 0.388735689 | 0.893392703 | 0.70592629 | | Asparagine \|\| id:638 | Inverse variance weighted | 2 | 0.115595736 | 0.571713012 | 0.83976671 | | X-12696 \|\| id:640 | Inverse variance weighted | 2 | -0.772918114 | 0.506221646 | 0.126801463 | | X-12704 \|\| id:641 | Wald ratio | 1 | 0.250485437 | 0.326213592 | 0.442572061 | | X-12712 \|\| id:642 | Wald ratio | 1 | 0.213225806 | 0.175483871 | 0.224338048 | | X-12728 \|\| id:646 | Inverse variance weighted | 4 | 0.001165733 | 0.04049965 | 0.977037032 | | X-12728 \|\| id:646 | MR Egger | 4 | 0.104517171 | 0.10466223 | 0.423183559 | | X-12728 \|\| id:646 | Weighted median | 4 | 0.014224964 | 0.048225698 | 0.768019493 | | X-12728 \|\| id:646 | Weighted mode | 4 | 0.019387308 | 0.050839368 | 0.728353143 | | X-12740 \|\| id:649 | Wald ratio | 1 | 0.37037037 | 0.323586745 | 0.25238388 | | X-12749 \|\| id:650 | Wald ratio | 1 | -0.738955823 | 1.248995984 | 0.554091769 | | Isovalerylcarnitine \|\| id:652 | Inverse variance weighted | 3 | -0.117920364 | 0.297528266 | 0.691859152 | | Isovalerylcarnitine \|\| id:652 | MR Egger | 3 | -3.018385093 | 4.129450326 | 0.598171051 | | Isovalerylcarnitine \|\| id:652 | Weighted median | 3 | -0.193055637 | 0.337010253 | 0.56674764 | | Isovalerylcarnitine \|\| id:652 | Weighted mode | 3 | -0.208581342 | 0.351776552 | 0.613340027 | | Stearoylcarnitine \|\| id:653 | Wald ratio | 1 | -1.214953271 | 0.742990654 | 0.102002911 | | 1-stearoylglycerophosphoethanolamine \|\| id:654 | Wald ratio | 1 | -0.43003413 | 0.679180887 | 0.526625358 | | Bradykinin, des-arg(9) \|\| id:656 | Inverse variance weighted | 3 | -0.081841744 | 0.074463927 | 0.271733575 | | Bradykinin, des-arg(9) \|\| id:656 | MR Egger | 3 | 0.160068092 | 0.239821178 | 0.625321814 | | Bradykinin, des-arg(9) \|\| id:656 | Weighted median | 3 | -0.058804791 | 0.078395381 | 0.453191291 | | Bradykinin, des-arg(9) \|\| id:656 | Weighted mode | 3 | -0.048745311 | 0.090708456 | 0.644791906 | | Waist circumference \|\| id:66 | Inverse variance weighted | 59 | -0.119298395 | 0.098700642 | 0.22678229 | | Waist circumference \|\| id:66 | MR Egger | 59 | -0.232115968 | 0.421939377 | 0.584388593 | | Waist circumference \|\| id:66 | Weighted median | 59 | -0.110915364 | 0.136343749 | 0.415932607 | | Waist circumference \|\| id:66 | Weighted mode | 59 | -0.12717207 | 0.315010595 | 0.687912593 | | X-12798 \|\| id:661 | Inverse variance weighted | 3 | -0.113570533 | 0.130921422 | 0.38568401 | | X-12798 \|\| id:661 | MR Egger | 3 | -0.01973693 | 0.1844452 | 0.932135462 | | X-12798 \|\| id:661 | Weighted median | 3 | -0.094579266 | 0.130884446 | 0.469915499 | | X-12798 \|\| id:661 | Weighted mode | 3 | -0.095260837 | 0.143870848 | 0.575978401 | | X-12844 \|\| id:665 | Inverse variance weighted | 3 | -0.288909275 | 0.710912607 | 0.684454516 | | X-12844 \|\| id:665 | MR Egger | 3 | 1.035346152 | 6.362964977 | 0.897312721 | | X-12844 \|\| id:665 | Weighted median | 3 | 0.225822206 | 0.561975288 | 0.687804327 | | X-12844 \|\| id:665 | Weighted mode | 3 | 0.256960383 | 0.590878522 | 0.706077219 | | X-12850 \|\| id:667 | Inverse variance weighted | 2 | -0.462343569 | 0.333204269 | 0.165268643 | | Waist circumference \|\| id:67 | Inverse variance weighted | 60 | -0.040907262 | 0.102107599 | 0.688693313 | | Waist circumference \|\| id:67 | MR Egger | 60 | -0.139244481 | 0.453104047 | 0.75970637 | | Waist circumference \|\| id:67 | Weighted median | 60 | 0.005635927 | 0.130132967 | 0.965455225 | | Waist circumference \|\| id:67 | Weighted mode | 60 | 0.147323113 | 0.298483518 | 0.623440842 | | X-12855 \|\| id:670 | Inverse variance weighted | 2 | -0.348891533 | 0.477289502 | 0.464788231 | | X-13069 \|\| id:673 | Wald ratio | 1 | -0.203367876 | 0.637305699 | 0.749646368 | | X-13215 \|\| id:675 | Inverse variance weighted | 2 | 0.923389555 | 0.931416162 | 0.321498909 | | Pro-hydroxy-pro \|\| id:678 | Wald ratio | 1 | -0.416058394 | 1.175182482 | 0.723310955 | | N2,N2-dimethylguanosine \|\| id:679 | Inverse variance weighted | 2 | 1.532148057 | 1.040124762 | 0.140739556 | | Cysteine-glutathione disulfide \|\| id:680 | Wald ratio | 1 | 0.221544715 | 0.365853659 | 0.544809923 | | 1-arachidonoylglycerophosphoethanolamine\* \|\| id:682 | Inverse variance weighted | 2 | -0.296538752 | 1.096969547 | 0.786909912 | | X-13429 \|\| id:683 | Inverse variance weighted | 3 | 0.135998575 | 0.127093408 | 0.28458875 | | X-13429 \|\| id:683 | MR Egger | 3 | 0.255578295 | 0.354967911 | 0.602732934 | | X-13429 \|\| id:683 | Weighted median | 3 | 0.152970578 | 0.130259171 | 0.240252648 | | X-13429 \|\| id:683 | Weighted mode | 3 | 0.155765548 | 0.137089546 | 0.373672357 | | X-13431--nonanoylcarnitine\* \|\| id:684 | Inverse variance weighted | 2 | -0.309685484 | 0.181106554 | 0.087272739 | | X-13435 \|\| id:685 | Inverse variance weighted | 2 | 0.027492233 | 0.421590243 | 0.94800617 | | X-13477 \|\| id:686 | Wald ratio | 1 | -1.184 | 0.756 | 0.117316415 | | 2-stearoylglycerophosphocholine\* \|\| id:689 | Wald ratio | 1 | -1.163822526 | 0.822525597 | 0.157086746 | | 2-linoleoylglycerophosphocholine\* \|\| id:690 | Wald ratio | 1 | -0.146341463 | 0.963414634 | 0.879266807 | | X-13496 \|\| id:691 | Inverse variance weighted | 2 | -0.665297503 | 1.289019209 | 0.605765773 | | X-13548 \|\| id:693 | Inverse variance weighted | 2 | -0.592837833 | 1.135131158 | 0.601486719 | | Hydroxyisovaleroyl carnitine \|\| id:698 | Inverse variance weighted | 2 | -0.376456513 | 0.641374337 | 0.557235355 | | Glutaroyl carnitine \|\| id:699 | Inverse variance weighted | 7 | 0.07182023 | 0.254744203 | 0.777996594 | | Glutaroyl carnitine \|\| id:699 | MR Egger | 7 | 1.328431322 | 1.094538764 | 0.279063695 | | Glutaroyl carnitine \|\| id:699 | Weighted median | 7 | 0.207509592 | 0.328419727 | 0.527489699 | | Glutaroyl carnitine \|\| id:699 | Weighted mode | 7 | 0.303498743 | 0.395590357 | 0.472060124 | | Coronary heart disease \|\| id:7 | Inverse variance weighted | 37 | 0.09759381 | 0.259619659 | 0.706983278 | | Coronary heart disease \|\| id:7 | MR Egger | 37 | 0.108268459 | 0.632274007 | 0.865023891 | | Coronary heart disease \|\| id:7 | Weighted median | 37 | -0.046600264 | 0.059283958 | 0.431837125 | | Coronary heart disease \|\| id:7 | Weighted mode | 37 | 0.03783274 | 0.073387801 | 0.609342581 | | X-13658 \|\| id:700 | Wald ratio | 1 | 0.175417661 | 0.262529833 | 0.50401754 | | X-13671 \|\| id:701 | Wald ratio | 1 | 0.573033708 | 0.893258427 | 0.521191754 | | 2-tetradecenoyl carnitine \|\| id:702 | Wald ratio | 1 | -0.86381323 | 0.638132296 | 0.175845342 | | X-13741 \|\| id:704 | Wald ratio | 1 | -0.141744548 | 0.392523364 | 0.718016387 | | 1-oleoylglycerophosphoethanolamine \|\| id:706 | Wald ratio | 1 | -0.093984962 | 0.718045113 | 0.895862284 | | 1-palmitoylglycerophosphoethanolamine \|\| id:707 | Inverse variance weighted | 2 | -0.798595905 | 0.992988312 | 0.421261298 | | Tetradecanedioate \|\| id:709 | Inverse variance weighted | 2 | 0.136930173 | 0.17823579 | 0.442336916 | | 2-hydroxypalmitate \|\| id:710 | Wald ratio | 1 | -0.638095238 | 1.638095238 | 0.696880511 | | Hexadecanedioate \|\| id:711 | Inverse variance weighted | 2 | 0.227777348 | 0.20372243 | 0.26353414 | | Dihomo-linolenate (20:3n3 or n6) \|\| id:712 | Inverse variance weighted | 2 | -0.701365033 | 0.542839221 | 0.196346453 | | X-13859 \|\| id:713 | Wald ratio | 1 | -0.555555556 | 1.490740741 | 0.709393466 | | X-14086 \|\| id:717 | Wald ratio | 1 | -1.33819242 | 0.451895044 | 0.00306353 | | X-14189--leucylalanine \|\| id:719 | Inverse variance weighted | 2 | -0.544929003 | 0.372655498 | 0.143662791 | | Waist-to-hip ratio \|\| id:72 | Inverse variance weighted | 29 | -0.170082114 | 0.137250112 | 0.215266652 | | Waist-to-hip ratio \|\| id:72 | MR Egger | 29 | -0.381698135 | 0.620942803 | 0.543894078 | | Waist-to-hip ratio \|\| id:72 | Weighted median | 29 | -0.284179365 | 0.202519227 | 0.160550751 | | Waist-to-hip ratio \|\| id:72 | Weighted mode | 29 | -0.217119183 | 0.316394033 | 0.498211517 | | X-14205--alpha-glutamyltyrosine \|\| id:720 | Wald ratio | 1 | -1.050343249 | 0.354691076 | 0.00306353 | | X-14208--phenylalanylserine \|\| id:721 | Inverse variance weighted | 2 | -0.516874007 | 0.220875188 | 0.019277647 | | X-14304--leucylalanine \|\| id:722 | Inverse variance weighted | 2 | -0.578222895 | 0.424988213 | 0.173652087 | | X-14473 \|\| id:725 | Wald ratio | 1 | -0.263657957 | 0.536817102 | 0.623320047 | | X-14625 \|\| id:728 | Wald ratio | 1 | -1.090301003 | 1.066889632 | 0.306807608 | | X-14626 \|\| id:729 | Inverse variance weighted | 2 | 0.422033958 | 0.364483832 | 0.246906943 | | Waist-to-hip ratio \|\| id:73 | Inverse variance weighted | 28 | -0.033598321 | 0.147237363 | 0.819497334 | | Waist-to-hip ratio \|\| id:73 | MR Egger | 28 | -0.361976644 | 0.678745303 | 0.598353861 | | Waist-to-hip ratio \|\| id:73 | Weighted median | 28 | -0.018697623 | 0.202987706 | 0.926608979 | | Waist-to-hip ratio \|\| id:73 | Weighted mode | 28 | -0.146288026 | 0.327542489 | 0.658709069 | | X-14662 \|\| id:732 | Wald ratio | 1 | 0.363256785 | 0.438413361 | 0.407346961 | | Octadecanedioate \|\| id:735 | Inverse variance weighted | 2 | 0.168223453 | 0.387875723 | 0.664503026 | | Dimethylarginine (SDMA + ADMA) \|\| id:739 | Wald ratio | 1 | -0.149659864 | 1.789115646 | 0.933334561 | | Succinylcarnitine \|\| id:742 | Inverse variance weighted | 6 | -0.588713825 | 0.51167143 | 0.249909158 | | Succinylcarnitine \|\| id:742 | MR Egger | 6 | -1.57086715 | 1.020293542 | 0.198490724 | | Succinylcarnitine \|\| id:742 | Weighted median | 6 | -0.727328004 | 0.409660642 | 0.075825218 | | Succinylcarnitine \|\| id:742 | Weighted mode | 6 | -1.17594959 | 0.412281649 | 0.035727415 | | Tryptophan betaine \|\| id:743 | Wald ratio | 1 | -0.251582278 | 0.16693038 | 0.131782719 | | 5alpha-androstan-3beta,17beta-diol disulfate \|\| id:746 | Inverse variance weighted | 3 | -0.213073603 | 0.143590325 | 0.137835601 | | 5alpha-androstan-3beta,17beta-diol disulfate \|\| id:746 | MR Egger | 3 | -0.54932998 | 0.301416535 | 0.319483449 | | 5alpha-androstan-3beta,17beta-diol disulfate \|\| id:746 | Weighted median | 3 | -0.252355405 | 0.160028634 | 0.114809546 | | 5alpha-androstan-3beta,17beta-diol disulfate \|\| id:746 | Weighted mode | 3 | -0.279091411 | 0.186145982 | 0.27254961 | | 4-androsten-3beta,17beta-diol disulfate 1\* \|\| id:747 | Inverse variance weighted | 2 | -0.111050494 | 0.269447176 | 0.680235357 | | 4-androsten-3beta,17beta-diol disulfate 2\* \|\| id:748 | Inverse variance weighted | 2 | 0.093011731 | 0.339602728 | 0.784173818 | | Palmitoyl sphingomyelin \|\| id:751 | Inverse variance weighted | 2 | -0.195485353 | 1.011434541 | 0.84674334 | | Cis-4-decenoyl carnitine \|\| id:753 | Inverse variance weighted | 2 | 0.285439172 | 0.264566009 | 0.280634155 | | Years of schooling \|\| id:755 | Inverse variance weighted | 4 | -0.493246474 | 0.314660974 | 0.116986438 | | Years of schooling \|\| id:755 | MR Egger | 4 | -1.629051556 | 4.465526822 | 0.750219692 | | Years of schooling \|\| id:755 | Weighted median | 4 | -0.467007277 | 0.368070695 | 0.204513201 | | Years of schooling \|\| id:755 | Weighted mode | 4 | -0.222800219 | 0.523820171 | 0.699257241 | | 2hr glucose \|\| id:756 | Wald ratio | 1 | -0.028461538 | 0.135384615 | 0.833490295 | | Fasting glucose \|\| id:757 | Inverse variance weighted | 9 | 0.413182734 | 0.210419428 | 0.049574763 | | Fasting glucose \|\| id:757 | MR Egger | 9 | -0.253460342 | 0.45905656 | 0.598035137 | | Fasting glucose \|\| id:757 | Weighted median | 9 | 0.292442368 | 0.194362875 | 0.132421669 | | Fasting glucose \|\| id:757 | Weighted mode | 9 | 0.290271213 | 0.182134745 | 0.149665234 | | HbA1C \|\| id:758 | Inverse variance weighted | 11 | 0.239368399 | 0.159422057 | 0.133232479 | | HbA1C \|\| id:758 | MR Egger | 11 | -0.084131397 | 0.371539076 | 0.825918273 | | HbA1C \|\| id:758 | Weighted median | 11 | 0.150716309 | 0.201120413 | 0.453626124 | | HbA1C \|\| id:758 | Weighted mode | 11 | 0.220367814 | 0.255674275 | 0.408930648 | | Corrected insulin response \|\| id:761 | Inverse variance weighted | 2 | 0.057318233 | 0.093506058 | 0.539883272 | | Corrected insulin response \|\| id:762 | Wald ratio | 1 | -0.015384615 | 0.124615385 | 0.901745389 | | Fasting proinsulin \|\| id:769 | Inverse variance weighted | 6 | 0.024244793 | 0.094744375 | 0.798030442 | | Fasting proinsulin \|\| id:769 | MR Egger | 6 | -0.103804852 | 0.206130637 | 0.641020052 | | Fasting proinsulin \|\| id:769 | Weighted median | 6 | -0.034127183 | 0.119247177 | 0.774733672 | | Fasting proinsulin \|\| id:769 | Weighted mode | 6 | -0.043326323 | 0.128613005 | 0.74989203 | | HOMA-B \|\| id:770 | Inverse variance weighted | 2 | -0.516290489 | 0.375305793 | 0.168929132 | | Fasting glucose \|\| id:772 | Wald ratio | 1 | 6.664285714 | 4.542857143 | 0.142381188 | | Fasting glucose \|\| id:773 | Inverse variance weighted | 19 | 0.232753575 | 0.196021481 | 0.235074569 | | Fasting glucose \|\| id:773 | MR Egger | 19 | 0.422884383 | 0.457457042 | 0.368202064 | | Fasting glucose \|\| id:773 | Weighted median | 19 | 0.296295857 | 0.184565068 | 0.108411647 | | Fasting glucose \|\| id:773 | Weighted mode | 19 | 0.314430974 | 0.188585656 | 0.112756458 | | Fasting insulin \|\| id:774 | Inverse variance weighted | 4 | -0.923759343 | 1.407522 | 0.511629904 | | Fasting insulin \|\| id:774 | MR Egger | 4 | -1.424192204 | 1.785245456 | 0.508680876 | | Fasting insulin \|\| id:774 | Weighted median | 4 | -1.05005769 | 0.835593016 | 0.208876184 | | Fasting insulin \|\| id:774 | Weighted mode | 4 | -1.152130648 | 0.858239168 | 0.272000326 | | Fasting insulin \|\| id:775 | Inverse variance weighted | 4 | 0.23379232 | 0.457595322 | 0.609410568 | | Fasting insulin \|\| id:775 | MR Egger | 4 | 1.004748953 | 2.515992671 | 0.728247242 | | Fasting insulin \|\| id:775 | Weighted median | 4 | 0.225928113 | 0.4922237 | 0.646237909 | | Fasting insulin \|\| id:775 | Weighted mode | 4 | 0.219657928 | 0.628752557 | 0.749906984 | | 2hr glucose \|\| id:776 | Inverse variance weighted | 7 | 0.116772569 | 0.07939389 | 0.141345091 | | 2hr glucose \|\| id:776 | MR Egger | 7 | -0.07011822 | 0.404400362 | 0.869147247 | | 2hr glucose \|\| id:776 | Weighted median | 7 | 0.110251951 | 0.098308484 | 0.262079475 | | 2hr glucose \|\| id:776 | Weighted mode | 7 | 0.119546469 | 0.141457225 | 0.430455552 | | Fasting glucose \|\| id:777 | Inverse variance weighted | 32 | 0.252853265 | 0.15946786 | 0.112828616 | | Fasting glucose \|\| id:777 | MR Egger | 32 | 0.251146515 | 0.34179692 | 0.468176978 | | Fasting glucose \|\| id:777 | Weighted median | 32 | 0.298441396 | 0.186893795 | 0.1102991 | | Fasting glucose \|\| id:777 | Weighted mode | 32 | 0.295789452 | 0.182919267 | 0.115999895 | | Fasting insulin \|\| id:778 | Inverse variance weighted | 14 | 0.385894362 | 0.290355259 | 0.183834081 | | Fasting insulin \|\| id:778 | MR Egger | 14 | 1.272035093 | 1.575757102 | 0.435229788 | | Fasting insulin \|\| id:778 | Weighted median | 14 | 0.563998441 | 0.369128672 | 0.126532832 | | Fasting insulin \|\| id:778 | Weighted mode | 14 | 0.59076347 | 0.568375911 | 0.317570299 | | Fasting insulin \|\| id:779 | Inverse variance weighted | 14 | 0.243871801 | 0.284192928 | 0.390825882 | | Fasting insulin \|\| id:779 | MR Egger | 14 | 1.178198447 | 1.624603495 | 0.482219217 | | Fasting insulin \|\| id:779 | Weighted median | 14 | 0.607438194 | 0.351331849 | 0.083816519 | | Fasting insulin \|\| id:779 | Weighted mode | 14 | 0.743344941 | 0.482856185 | 0.147668499 | | Waist-to-hip ratio \|\| id:78 | Inverse variance weighted | 35 | 0.060154668 | 0.111547726 | 0.589698549 | | Waist-to-hip ratio \|\| id:78 | MR Egger | 35 | -0.744649128 | 0.498775459 | 0.14494912 | | Waist-to-hip ratio \|\| id:78 | Weighted median | 35 | -0.008765038 | 0.157487949 | 0.955616417 | | Waist-to-hip ratio \|\| id:78 | Weighted mode | 35 | -0.061515115 | 0.314887736 | 0.846277294 | | HDL cholesterol \|\| id:780 | Inverse variance weighted | 40 | -0.08039576 | 0.103390741 | 0.436809881 | | HDL cholesterol \|\| id:780 | MR Egger | 40 | -0.320520647 | 0.183735944 | 0.089162815 | | HDL cholesterol \|\| id:780 | Weighted median | 40 | 0.000358822 | 0.076233398 | 0.996244461 | | HDL cholesterol \|\| id:780 | Weighted mode | 40 | -0.005401486 | 0.075060538 | 0.943000146 | | LDL cholesterol \|\| id:781 | Inverse variance weighted | 36 | 0.36644429 | 0.148977031 | 0.013903893 | | LDL cholesterol \|\| id:781 | MR Egger | 36 | 0.534441211 | 0.216694355 | 0.018849629 | | LDL cholesterol \|\| id:781 | Weighted median | 36 | 0.087185921 | 0.077666591 | 0.261621609 | | LDL cholesterol \|\| id:781 | Weighted mode | 36 | -0.006429178 | 0.284057158 | 0.982071253 | | Total cholesterol \|\| id:782 | Inverse variance weighted | 40 | 0.336262583 | 0.177520998 | 0.058196742 | | Total cholesterol \|\| id:782 | MR Egger | 40 | 0.638808559 | 0.303714515 | 0.042113618 | | Total cholesterol \|\| id:782 | Weighted median | 40 | 0.050537624 | 0.084206433 | 0.548397304 | | Total cholesterol \|\| id:782 | Weighted mode | 40 | -0.012136451 | 0.096368249 | 0.900427797 | | Triglycerides \|\| id:783 | Inverse variance weighted | 26 | 0.155410212 | 0.216837834 | 0.473552007 | | Triglycerides \|\| id:783 | MR Egger | 26 | 0.176640848 | 0.406138817 | 0.667501145 | | Triglycerides \|\| id:783 | Weighted median | 26 | -0.019583524 | 0.087954406 | 0.823803712 | | Triglycerides \|\| id:783 | Weighted mode | 26 | -0.01002645 | 0.08793712 | 0.910133957 | | Urate \|\| id:789 | Inverse variance weighted | 3 | 0.022462689 | 0.033640777 | 0.504311037 | | Urate \|\| id:789 | MR Egger | 3 | 0.008359878 | 0.041015522 | 0.871996055 | | Urate \|\| id:789 | Weighted median | 3 | 0.019323348 | 0.034431322 | 0.574651491 | | Urate \|\| id:789 | Weighted mode | 3 | 0.012865559 | 0.035744023 | 0.753350121 | | Waist-to-hip ratio \|\| id:79 | Inverse variance weighted | 35 | 0.116554774 | 0.118247072 | 0.324286016 | | Waist-to-hip ratio \|\| id:79 | MR Egger | 35 | -0.569694339 | 0.568465267 | 0.323557573 | | Waist-to-hip ratio \|\| id:79 | Weighted median | 35 | 0.092398423 | 0.158172724 | 0.55911163 | | Waist-to-hip ratio \|\| id:79 | Weighted mode | 35 | 0.087743702 | 0.298331334 | 0.770458217 | | Urate \|\| id:792 | Inverse variance weighted | 3 | 0.004224752 | 0.013770388 | 0.758995762 | | Urate \|\| id:792 | MR Egger | 3 | -0.002989175 | 0.021422157 | 0.911738126 | | Urate \|\| id:792 | Weighted median | 3 | 0.003969783 | 0.014555862 | 0.785062711 | | Urate \|\| id:792 | Weighted mode | 3 | 0.000246062 | 0.01379199 | 0.987385576 | | Urate \|\| id:795 | Inverse variance weighted | 4 | 0.097363145 | 0.054798529 | 0.075609809 | | Urate \|\| id:795 | MR Egger | 4 | 0.015289171 | 0.10678601 | 0.899274315 | | Urate \|\| id:795 | Weighted median | 4 | 0.084555289 | 0.060578284 | 0.162774131 | | Urate \|\| id:795 | Weighted mode | 4 | 0.082861463 | 0.067340714 | 0.306199807 | | Myocardial infarction \|\| id:798 | Inverse variance weighted | 23 | 0.036103296 | 0.11281674 | 0.748955303 | | Myocardial infarction \|\| id:798 | MR Egger | 23 | 0.186172946 | 0.279906178 | 0.513208933 | | Myocardial infarction \|\| id:798 | Weighted median | 23 | 0.000232492 | 0.066181298 | 0.997197074 | | Myocardial infarction \|\| id:798 | Weighted mode | 23 | 0.0467067 | 0.07523267 | 0.541090688 | | Coronary heart disease \|\| id:8 | Inverse variance weighted | 13 | -0.02249775 | 0.042466186 | 0.596264249 | | Coronary heart disease \|\| id:8 | MR Egger | 13 | 0.033822599 | 0.127846877 | 0.796243296 | | Coronary heart disease \|\| id:8 | Weighted median | 13 | -0.008097984 | 0.057175721 | 0.887369695 | | Coronary heart disease \|\| id:8 | Weighted mode | 13 | 0.079702312 | 0.072389334 | 0.292481892 | | Bipolar disorder \|\| id:800 | Inverse variance weighted | 4 | -0.015673649 | 0.058762728 | 0.789678801 | | Bipolar disorder \|\| id:800 | MR Egger | 4 | -0.125568827 | 0.222218525 | 0.628958214 | | Bipolar disorder \|\| id:800 | Weighted median | 4 | -0.017207854 | 0.066658135 | 0.796290491 | | Bipolar disorder \|\| id:800 | Weighted mode | 4 | 0.043882075 | 0.103373875 | 0.699805652 | | Bipolar disorder \|\| id:801 | Inverse variance weighted | 4 | -0.015673649 | 0.058762728 | 0.789678801 | | Bipolar disorder \|\| id:801 | MR Egger | 4 | -0.125568827 | 0.222218525 | 0.628958214 | | Bipolar disorder \|\| id:801 | Weighted median | 4 | -0.017207854 | 0.065659477 | 0.793261898 | | Bipolar disorder \|\| id:801 | Weighted mode | 4 | 0.043882075 | 0.094674061 | 0.674559062 | | PGC cross-disorder traits \|\| id:803 | Inverse variance weighted | 4 | 0.139057304 | 0.10788754 | 0.197429456 | | PGC cross-disorder traits \|\| id:803 | MR Egger | 4 | 0.408329132 | 0.630033861 | 0.583384904 | | PGC cross-disorder traits \|\| id:803 | Weighted median | 4 | 0.197214606 | 0.122508236 | 0.107440013 | | PGC cross-disorder traits \|\| id:803 | Weighted mode | 4 | 0.209009312 | 0.164600513 | 0.293705244 | | Autism \|\| id:806 | Wald ratio | 1 | -0.076148815 | 0.098175332 | 0.43796097 | | Parkinson's disease \|\| id:812 | Inverse variance weighted | 4 | 0.025532479 | 0.060356254 | 0.672273701 | | Parkinson's disease \|\| id:812 | MR Egger | 4 | -0.071204644 | 0.350365543 | 0.857756224 | | Parkinson's disease \|\| id:812 | Weighted median | 4 | 0.012646184 | 0.040124747 | 0.752631303 | | Parkinson's disease \|\| id:812 | Weighted mode | 4 | -0.035612055 | 0.087010424 | 0.709797976 | | Ischaemic stroke \|\| id:814 | Wald ratio | 1 | -0.002392715 | 0.009064709 | 0.791811211 | | Systemic lupus erythematosus \|\| id:815 | Inverse variance weighted | 2 | -0.011411984 | 0.03647352 | 0.75436873 | | Neuroblastoma \|\| id:816 | Inverse variance weighted | 3 | -0.063121558 | 0.04059461 | 0.119964025 | | Neuroblastoma \|\| id:816 | MR Egger | 3 | -0.366030621 | 0.435685763 | 0.555172585 | | Neuroblastoma \|\| id:816 | Weighted median | 3 | -0.047007337 | 0.039731279 | 0.236756941 | | Neuroblastoma \|\| id:816 | Weighted mode | 3 | -0.018335453 | 0.060838148 | 0.79157191 | | Inflammatory bowel disease \|\| id:819 | Wald ratio | 1 | Inf | Inf | NA | | Rheumatoid arthritis \|\| id:831 | Inverse variance weighted | 7 | -0.003181378 | 0.038243408 | 0.933702348 | | Rheumatoid arthritis \|\| id:831 | MR Egger | 7 | -0.309120217 | 0.204650899 | 0.191311764 | | Rheumatoid arthritis \|\| id:831 | Weighted median | 7 | -0.013491267 | 0.048670492 | 0.781629589 | | Rheumatoid arthritis \|\| id:831 | Weighted mode | 7 | -0.02826416 | 0.055205752 | 0.626958418 | | Rheumatoid arthritis \|\| id:832 | Inverse variance weighted | 34 | 0.007562616 | 0.023552873 | 0.748141397 | | Rheumatoid arthritis \|\| id:832 | MR Egger | 34 | -0.004303713 | 0.045774438 | 0.9256795 | | Rheumatoid arthritis \|\| id:832 | Weighted median | 34 | 0.002512343 | 0.031774424 | 0.936978473 | | Rheumatoid arthritis \|\| id:832 | Weighted mode | 34 | 0.020518882 | 0.035790498 | 0.570324544 | | Rheumatoid arthritis \|\| id:833 | Inverse variance weighted | 43 | 0.001700282 | 0.021669376 | 0.937458361 | | Rheumatoid arthritis \|\| id:833 | MR Egger | 43 | 0.036860349 | 0.045275501 | 0.420271387 | | Rheumatoid arthritis \|\| id:833 | Weighted median | 43 | 0.025201545 | 0.031469908 | 0.423239303 | | Rheumatoid arthritis \|\| id:833 | Weighted mode | 43 | 0.03110588 | 0.039050788 | 0.430192565 | | Rheumatoid arthritis \|\| id:834 | Inverse variance weighted | 6 | 0.014601883 | 0.027404562 | 0.594153526 | | Rheumatoid arthritis \|\| id:834 | MR Egger | 6 | 0.044804725 | 0.047750288 | 0.401207779 | | Rheumatoid arthritis \|\| id:834 | Weighted median | 6 | 0.030998067 | 0.033395453 | 0.35329751 | | Rheumatoid arthritis \|\| id:834 | Weighted mode | 6 | 0.042266571 | 0.036862389 | 0.303436296 | | Body mass index \|\| id:835 | Inverse variance weighted | 65 | 0.030136623 | 0.105992294 | 0.776158698 | | Body mass index \|\| id:835 | MR Egger | 65 | -0.402407287 | 0.302091464 | 0.187635773 | | Body mass index \|\| id:835 | Weighted median | 65 | 0.070153293 | 0.132922243 | 0.597654172 | | Body mass index \|\| id:835 | Weighted mode | 65 | 0.291275323 | 0.248224465 | 0.244969925 | | College completion \|\| id:836 | Inverse variance weighted | 3 | -0.166122672 | 0.166616001 | 0.318745517 | | College completion \|\| id:836 | MR Egger | 3 | 2.062965219 | 1.654876836 | 0.430400153 | | College completion \|\| id:836 | Weighted median | 3 | -0.30672708 | 0.191656964 | 0.109510714 | | College completion \|\| id:836 | Weighted mode | 3 | -0.352187721 | 0.262272705 | 0.311431852 | | Years of schooling \|\| id:837 | Inverse variance weighted | 4 | -0.332106736 | 0.477554358 | 0.48678441 | | Years of schooling \|\| id:837 | MR Egger | 4 | -10.8383204 | 4.763595967 | 0.150693866 | | Years of schooling \|\| id:837 | Weighted median | 4 | -0.534449486 | 0.43272503 | 0.216801199 | | Years of schooling \|\| id:837 | Weighted mode | 4 | -0.865558009 | 0.631457444 | 0.264009872 | | Acetoacetate \|\| id:838 | Wald ratio | 1 | -0.067733271 | 0.32114913 | 0.83295821 | | Acetate \|\| id:839 | Wald ratio | 1 | -0.231271886 | 0.898905822 | 0.796961432 | | Alanine \|\| id:840 | Inverse variance weighted | 5 | -0.045281281 | 0.217105082 | 0.834785106 | | Alanine \|\| id:840 | MR Egger | 5 | -0.678488036 | 1.087402812 | 0.57688498 | | Alanine \|\| id:840 | Weighted median | 5 | -0.004855271 | 0.144993271 | 0.973286886 | | Alanine \|\| id:840 | Weighted mode | 5 | -0.016194235 | 0.167903552 | 0.927802628 | | Albumin \|\| id:841 | Inverse variance weighted | 2 | 0.176027004 | 0.206999692 | 0.395117595 | | Apolipoprotein A-I \|\| id:842 | Inverse variance weighted | 9 | -0.148936432 | 0.080365535 | 0.06384831 | | Apolipoprotein A-I \|\| id:842 | MR Egger | 9 | 0.080246203 | 0.216661892 | 0.722055887 | | Apolipoprotein A-I \|\| id:842 | Weighted median | 9 | -0.079267328 | 0.079160377 | 0.316657111 | | Apolipoprotein A-I \|\| id:842 | Weighted mode | 9 | -0.006325166 | 0.08593647 | 0.943133484 | | Apolipoprotein B \|\| id:843 | Inverse variance weighted | 13 | 0.449540532 | 0.266731034 | 0.091917172 | | Apolipoprotein B \|\| id:843 | MR Egger | 13 | 1.135146211 | 0.472059237 | 0.034942647 | | Apolipoprotein B \|\| id:843 | Weighted median | 13 | 0.064510658 | 0.083257512 | 0.438438417 | | Apolipoprotein B \|\| id:843 | Weighted mode | 13 | 0.037500308 | 0.091754589 | 0.689957559 | | Ratio of bisallylic groups to double bonds \|\| id:844 | Inverse variance weighted | 5 | 0.025852961 | 0.051283929 | 0.614181072 | | Ratio of bisallylic groups to double bonds \|\| id:844 | MR Egger | 5 | 0.009324631 | 0.107954837 | 0.936610106 | | Ratio of bisallylic groups to double bonds \|\| id:844 | Weighted median | 5 | 0.029214403 | 0.041755373 | 0.484142066 | | Ratio of bisallylic groups to double bonds \|\| id:844 | Weighted mode | 5 | 0.02887562 | 0.04222323 | 0.531613496 | | Ratio of bisallylic groups to total fatty acids \|\| id:845 | Inverse variance weighted | 5 | 0.016624257 | 0.047241572 | 0.724914083 | | Ratio of bisallylic groups to total fatty acids \|\| id:845 | MR Egger | 5 | 0.058450808 | 0.091377655 | 0.567890128 | | Ratio of bisallylic groups to total fatty acids \|\| id:845 | Weighted median | 5 | 0.031628819 | 0.045712906 | 0.488999318 | | Ratio of bisallylic groups to total fatty acids \|\| id:845 | Weighted mode | 5 | 0.029194255 | 0.044334749 | 0.546193109 | | 3-hydroxybutyrate \|\| id:846 | Wald ratio | 1 | -0.125716806 | 0.23268637 | 0.589000942 | | Average number of methylene groups per double bond \|\| id:847 | Inverse variance weighted | 5 | -0.113696791 | 0.230795416 | 0.622273908 | | Average number of methylene groups per double bond \|\| id:847 | MR Egger | 5 | -0.123075881 | 0.52965137 | 0.831199541 | | Average number of methylene groups per double bond \|\| id:847 | Weighted median | 5 | -0.025992439 | 0.049979512 | 0.603020448 | | Average number of methylene groups per double bond \|\| id:847 | Weighted mode | 5 | -0.032650618 | 0.048283046 | 0.535975883 | | Average number of methylene groups in a fatty acid chain \|\| id:848 | Inverse variance weighted | 3 | -0.185549977 | 0.440558257 | 0.673630856 | | Average number of methylene groups in a fatty acid chain \|\| id:848 | MR Egger | 3 | 0.044838303 | 1.768480843 | 0.983862513 | | Average number of methylene groups in a fatty acid chain \|\| id:848 | Weighted median | 3 | -0.029234978 | 0.069846603 | 0.675537898 | | Average number of methylene groups in a fatty acid chain \|\| id:848 | Weighted mode | 3 | -0.033625171 | 0.066416111 | 0.66295279 | | Citrate \|\| id:849 | Inverse variance weighted | 4 | -0.188724708 | 0.097030547 | 0.051774614 | | Citrate \|\| id:849 | MR Egger | 4 | 0.016479033 | 0.762894628 | 0.984727803 | | Citrate \|\| id:849 | Weighted median | 4 | -0.183693615 | 0.114707517 | 0.109286428 | | Citrate \|\| id:849 | Weighted mode | 4 | -0.181755558 | 0.129610539 | 0.255384023 | | Extreme body mass index \|\| id:85 | Inverse variance weighted | 7 | 0.013600751 | 0.054005615 | 0.801165069 | | Extreme body mass index \|\| id:85 | MR Egger | 7 | 0.243943141 | 0.255725623 | 0.383929421 | | Extreme body mass index \|\| id:85 | Weighted median | 7 | 0.015448453 | 0.045980953 | 0.736889674 | | Extreme body mass index \|\| id:85 | Weighted mode | 7 | 0.011503907 | 0.05726726 | 0.847428151 | | Creatinine \|\| id:850 | Inverse variance weighted | 5 | -0.098890872 | 0.181410846 | 0.585670263 | | Creatinine \|\| id:850 | MR Egger | 5 | 0.756475602 | 1.201808001 | 0.573726577 | | Creatinine \|\| id:850 | Weighted median | 5 | 0.169184502 | 0.151420416 | 0.2638591 | | Creatinine \|\| id:850 | Weighted mode | 5 | 0.171024527 | 0.186671344 | 0.411410521 | | Average number of double bonds in a fatty acid chain \|\| id:851 | Inverse variance weighted | 5 | 0.007472527 | 0.060375849 | 0.901499897 | | Average number of double bonds in a fatty acid chain \|\| id:851 | MR Egger | 5 | 0.121260967 | 0.127524068 | 0.411812943 | | Average number of double bonds in a fatty acid chain \|\| id:851 | Weighted median | 5 | 0.018567999 | 0.056029047 | 0.740342727 | | Average number of double bonds in a fatty acid chain \|\| id:851 | Weighted mode | 5 | 0.027064539 | 0.055833005 | 0.65320871 | | 22:6, docosahexaenoic acid \|\| id:852 | Inverse variance weighted | 4 | 0.017157071 | 0.100498138 | 0.864443712 | | 22:6, docosahexaenoic acid \|\| id:852 | MR Egger | 4 | -0.318040982 | 0.60798797 | 0.653081506 | | 22:6, docosahexaenoic acid \|\| id:852 | Weighted median | 4 | 0.02703798 | 0.104045195 | 0.794965871 | | 22:6, docosahexaenoic acid \|\| id:852 | Weighted mode | 4 | 0.028636078 | 0.130625186 | 0.840544469 | | Free cholesterol to esterified cholesterol ratio \|\| id:853 | Inverse variance weighted | 8 | 0.377747924 | 0.146586899 | 0.009967477 | | Free cholesterol to esterified cholesterol ratio \|\| id:853 | MR Egger | 8 | 0.736291979 | 0.238498708 | 0.021464653 | | Free cholesterol to esterified cholesterol ratio \|\| id:853 | Weighted median | 8 | 0.147816833 | 0.090672124 | 0.103051925 | | Free cholesterol to esterified cholesterol ratio \|\| id:853 | Weighted mode | 8 | 0.056622804 | 0.089745665 | 0.548127796 | | Description of average fatty acid chain length, not actual carbon number \|\| id:854 | Wald ratio | 1 | 0.374414977 | 0.229167787 | 0.102300261 | | Omega-3 fatty acids \|\| id:855 | Inverse variance weighted | 5 | 0.0584919 | 0.070969856 | 0.409837574 | | Omega-3 fatty acids \|\| id:855 | MR Egger | 5 | -0.049381592 | 0.267770721 | 0.865448009 | | Omega-3 fatty acids \|\| id:855 | Weighted median | 5 | 0.028826181 | 0.084011554 | 0.731506962 | | Omega-3 fatty acids \|\| id:855 | Weighted mode | 5 | 0.058229446 | 0.099741137 | 0.590687168 | | Omega-6 fatty acids \|\| id:856 | Inverse variance weighted | 7 | 0.345266051 | 0.223808569 | 0.1229073 | | Omega-6 fatty acids \|\| id:856 | MR Egger | 7 | 1.143679881 | 0.528328297 | 0.08269308 | | Omega-6 fatty acids \|\| id:856 | Weighted median | 7 | 0.022901811 | 0.091592621 | 0.802556487 | | Omega-6 fatty acids \|\| id:856 | Weighted mode | 7 | 0.045761843 | 0.102838423 | 0.671932019 | | Omega-9 and saturated fatty acids \|\| id:857 | Inverse variance weighted | 4 | -0.057238543 | 0.081939934 | 0.484837865 | | Omega-9 and saturated fatty acids \|\| id:857 | MR Egger | 4 | 0.210185635 | 0.333162415 | 0.592599528 | | Omega-9 and saturated fatty acids \|\| id:857 | Weighted median | 4 | -0.017464989 | 0.098536601 | 0.859316994 | | Omega-9 and saturated fatty acids \|\| id:857 | Weighted mode | 4 | -0.016989792 | 0.107983216 | 0.884972073 | | Free cholesterol \|\| id:858 | Inverse variance weighted | 8 | 0.274829023 | 0.175987177 | 0.118372274 | | Free cholesterol \|\| id:858 | MR Egger | 8 | 0.612236042 | 0.422033384 | 0.197060028 | | Free cholesterol \|\| id:858 | Weighted median | 8 | 0.039533725 | 0.076713128 | 0.606311976 | | Free cholesterol \|\| id:858 | Weighted mode | 8 | 0.028451138 | 0.075433576 | 0.717223043 | | Glucose \|\| id:859 | Inverse variance weighted | 3 | 0.099706078 | 0.103510706 | 0.335425032 | | Glucose \|\| id:859 | MR Egger | 3 | 0.260972054 | 0.633421429 | 0.751201682 | | Glucose \|\| id:859 | Weighted median | 3 | 0.186435668 | 0.118423304 | 0.11541448 | | Glucose \|\| id:859 | Weighted mode | 3 | 0.187517953 | 0.135269532 | 0.299987738 | | Extreme height \|\| id:86 | Inverse variance weighted | 42 | -0.007283862 | 0.015233693 | 0.632549439 | | Extreme height \|\| id:86 | MR Egger | 42 | -0.204434814 | 0.063140198 | 0.002423946 | | Extreme height \|\| id:86 | Weighted median | 42 | -0.011190601 | 0.019701486 | 0.570029549 | | Extreme height \|\| id:86 | Weighted mode | 42 | 0.008280207 | 0.040072474 | 0.837320958 | | Glutamine \|\| id:860 | Inverse variance weighted | 5 | -0.192007767 | 0.07812681 | 0.013985232 | | Glutamine \|\| id:860 | MR Egger | 5 | -0.253238815 | 0.149540073 | 0.188944264 | | Glutamine \|\| id:860 | Weighted median | 5 | -0.206806329 | 0.088109913 | 0.018918129 | | Glutamine \|\| id:860 | Weighted mode | 5 | -0.209188949 | 0.097081354 | 0.097457698 | | Glycoproteins \|\| id:862 | Inverse variance weighted | 10 | -0.036291351 | 0.034138311 | 0.287751051 | | Glycoproteins \|\| id:862 | MR Egger | 10 | -0.00280325 | 0.050409731 | 0.957016793 | | Glycoproteins \|\| id:862 | Weighted median | 10 | -0.028815542 | 0.037363104 | 0.44057069 | | Glycoproteins \|\| id:862 | Weighted mode | 10 | -0.025612018 | 0.037506345 | 0.511880877 | | Glycoprotein acetyls \|\| id:863 | Inverse variance weighted | 6 | 0.08425792 | 0.107641863 | 0.433767108 | | Glycoprotein acetyls \|\| id:863 | MR Egger | 6 | 0.562203592 | 0.375443229 | 0.208630189 | | Glycoprotein acetyls \|\| id:863 | Weighted median | 6 | 0.081758493 | 0.123583151 | 0.508248979 | | Glycoprotein acetyls \|\| id:863 | Weighted mode | 6 | -0.100650352 | 0.176043263 | 0.592242687 | | Total cholesterol in HDL \|\| id:864 | Inverse variance weighted | 11 | -0.107320367 | 0.075941364 | 0.157596804 | | Total cholesterol in HDL \|\| id:864 | MR Egger | 11 | 0.076532997 | 0.185617295 | 0.689755785 | | Total cholesterol in HDL \|\| id:864 | Weighted median | 11 | -0.029786194 | 0.071027993 | 0.674954132 | | Total cholesterol in HDL \|\| id:864 | Weighted mode | 11 | -0.021771749 | 0.069769212 | 0.761408988 | | Mean diameter for HDL particles \|\| id:865 | Inverse variance weighted | 9 | -0.14987272 | 0.140479725 | 0.286033384 | | Mean diameter for HDL particles \|\| id:865 | MR Egger | 9 | 0.067344426 | 0.374577113 | 0.86241286 | | Mean diameter for HDL particles \|\| id:865 | Weighted median | 9 | -0.045651094 | 0.055419618 | 0.410089988 | | Mean diameter for HDL particles \|\| id:865 | Weighted mode | 9 | -0.034435177 | 0.049874048 | 0.509447659 | | Histidine \|\| id:866 | Inverse variance weighted | 3 | 0.021383209 | 0.119771659 | 0.858304306 | | Histidine \|\| id:866 | MR Egger | 3 | 6.20345853 | 5.695554093 | 0.472842633 | | Histidine \|\| id:866 | Weighted median | 3 | 0.048608259 | 0.137945699 | 0.724558989 | | Histidine \|\| id:866 | Weighted mode | 3 | 0.071031192 | 0.163421349 | 0.706217954 | | Total cholesterol in IDL \|\| id:867 | Inverse variance weighted | 14 | 0.158478382 | 0.149402392 | 0.288804155 | | Total cholesterol in IDL \|\| id:867 | MR Egger | 14 | 0.617944026 | 0.226929811 | 0.018502621 | | Total cholesterol in IDL \|\| id:867 | Weighted median | 14 | 0.053873476 | 0.07736899 | 0.48622925 | | Total cholesterol in IDL \|\| id:867 | Weighted mode | 14 | 0.030958307 | 0.098021913 | 0.75714449 | | Free cholesterol in IDL \|\| id:868 | Inverse variance weighted | 14 | 0.158624464 | 0.153754823 | 0.302226048 | | Free cholesterol in IDL \|\| id:868 | MR Egger | 14 | 0.573305691 | 0.246492386 | 0.038357731 | | Free cholesterol in IDL \|\| id:868 | Weighted median | 14 | 0.062971134 | 0.081303424 | 0.438623304 | | Free cholesterol in IDL \|\| id:868 | Weighted mode | 14 | 0.011845087 | 0.104808725 | 0.91174429 | | Total lipids in IDL \|\| id:869 | Inverse variance weighted | 15 | 0.14843733 | 0.145226712 | 0.306729964 | | Total lipids in IDL \|\| id:869 | MR Egger | 15 | 0.604325605 | 0.241612744 | 0.026527892 | | Total lipids in IDL \|\| id:869 | Weighted median | 15 | 0.053125112 | 0.076855377 | 0.489417995 | | Total lipids in IDL \|\| id:869 | Weighted mode | 15 | 0.036885286 | 0.09113472 | 0.691789447 | | Extreme waist-to-hip ratio \|\| id:87 | Inverse variance weighted | 2 | -0.082700785 | 0.059239956 | 0.162705312 | | Concentration of IDL particles \|\| id:870 | Inverse variance weighted | 13 | 0.146614323 | 0.161611104 | 0.364298655 | | Concentration of IDL particles \|\| id:870 | MR Egger | 13 | 0.699845902 | 0.279647883 | 0.029370491 | | Concentration of IDL particles \|\| id:870 | Weighted median | 13 | 0.051779222 | 0.076161753 | 0.496594 | | Concentration of IDL particles \|\| id:870 | Weighted mode | 13 | 0.028135522 | 0.086698728 | 0.751131128 | | Phospholipids in IDL \|\| id:871 | Inverse variance weighted | 15 | 0.152178562 | 0.148788815 | 0.306410804 | | Phospholipids in IDL \|\| id:871 | MR Egger | 15 | 0.604568928 | 0.24117673 | 0.026252579 | | Phospholipids in IDL \|\| id:871 | Weighted median | 15 | 0.073653121 | 0.083138852 | 0.375668748 | | Phospholipids in IDL \|\| id:871 | Weighted mode | 15 | 0.046236612 | 0.091760332 | 0.622178531 | | Triglycerides in IDL \|\| id:872 | Inverse variance weighted | 13 | 0.253977805 | 0.299305828 | 0.396128308 | | Triglycerides in IDL \|\| id:872 | MR Egger | 13 | 0.15600398 | 0.88303811 | 0.86298044 | | Triglycerides in IDL \|\| id:872 | Weighted median | 13 | -0.116347059 | 0.084658678 | 0.16934623 | | Triglycerides in IDL \|\| id:872 | Weighted mode | 13 | -0.174657067 | 0.091243404 | 0.079740365 | | Isoleucine \|\| id:873 | Wald ratio | 1 | -0.009337286 | 0.187912883 | 0.960369871 | | Total cholesterol in large HDL \|\| id:874 | Inverse variance weighted | 11 | -0.470692798 | 0.710043707 | 0.50739025 | | Total cholesterol in large HDL \|\| id:874 | MR Egger | 11 | 0.775876837 | 1.797067142 | 0.676084303 | | Total cholesterol in large HDL \|\| id:874 | Weighted median | 11 | -0.06269406 | 0.064773184 | 0.33309358 | | Total cholesterol in large HDL \|\| id:874 | Weighted mode | 11 | -0.049268487 | 0.058865491 | 0.422161907 | | Cholesterol esters in large HDL \|\| id:875 | Inverse variance weighted | 9 | -0.465404607 | 0.822731728 | 0.57160991 | | Cholesterol esters in large HDL \|\| id:875 | MR Egger | 9 | 1.077818631 | 2.153501235 | 0.632075323 | | Cholesterol esters in large HDL \|\| id:875 | Weighted median | 9 | -0.073955198 | 0.066129493 | 0.263422191 | | Cholesterol esters in large HDL \|\| id:875 | Weighted mode | 9 | -0.075390831 | 0.06647575 | 0.289586461 | | Free cholesterol in large HDL \|\| id:876 | Inverse variance weighted | 11 | -0.42802024 | 0.735532165 | 0.560621152 | | Free cholesterol in large HDL \|\| id:876 | MR Egger | 11 | 1.247819404 | 1.819021312 | 0.510006716 | | Free cholesterol in large HDL \|\| id:876 | Weighted median | 11 | -0.071582489 | 0.063214906 | 0.257480069 | | Free cholesterol in large HDL \|\| id:876 | Weighted mode | 11 | -0.091710296 | 0.061497343 | 0.166740795 | | Total lipids in large HDL \|\| id:877 | Inverse variance weighted | 7 | -0.36714531 | 0.893210655 | 0.681043202 | | Total lipids in large HDL \|\| id:877 | MR Egger | 7 | 2.788004486 | 2.919824932 | 0.383502966 | | Total lipids in large HDL \|\| id:877 | Weighted median | 7 | -0.022929857 | 0.062044243 | 0.71170091 | | Total lipids in large HDL \|\| id:877 | Weighted mode | 7 | -0.016966023 | 0.069980046 | 0.816513168 | | Concentration of large HDL particles \|\| id:878 | Inverse variance weighted | 7 | -0.361632395 | 0.890156705 | 0.684553774 | | Concentration of large HDL particles \|\| id:878 | MR Egger | 7 | 2.697329952 | 2.854654297 | 0.388102249 | | Concentration of large HDL particles \|\| id:878 | Weighted median | 7 | -0.025717564 | 0.060808099 | 0.672346397 | | Concentration of large HDL particles \|\| id:878 | Weighted mode | 7 | -0.032719153 | 0.064011095 | 0.627505825 | | Phospholipids in large HDL \|\| id:879 | Inverse variance weighted | 7 | -0.380852872 | 0.929812152 | 0.682097965 | | Phospholipids in large HDL \|\| id:879 | MR Egger | 7 | 2.68116252 | 2.949069027 | 0.404959768 | | Phospholipids in large HDL \|\| id:879 | Weighted median | 7 | -0.018684494 | 0.061771168 | 0.762286776 | | Phospholipids in large HDL \|\| id:879 | Weighted mode | 7 | -0.004760139 | 0.070433068 | 0.948312779 | | Total cholesterol in large LDL \|\| id:880 | Inverse variance weighted | 16 | 0.178338421 | 0.135463736 | 0.188005256 | | Total cholesterol in large LDL \|\| id:880 | MR Egger | 16 | 0.55599928 | 0.198957838 | 0.014332996 | | Total cholesterol in large LDL \|\| id:880 | Weighted median | 16 | 0.127009778 | 0.081397705 | 0.118674673 | | Total cholesterol in large LDL \|\| id:880 | Weighted mode | 16 | 0.024041573 | 0.169327768 | 0.88898331 | | Cholesterol esters in large VLDL \|\| id:881 | Inverse variance weighted | 17 | 0.18447513 | 0.128279875 | 0.15041488 | | Cholesterol esters in large VLDL \|\| id:881 | MR Egger | 17 | 0.535581474 | 0.195167397 | 0.015060403 | | Cholesterol esters in large VLDL \|\| id:881 | Weighted median | 17 | 0.144616015 | 0.080229515 | 0.071462242 | | Cholesterol esters in large VLDL \|\| id:881 | Weighted mode | 17 | 0.024571655 | 0.14345402 | 0.866146457 | | Free cholesterol in large LDL \|\| id:882 | Inverse variance weighted | 14 | 0.194212929 | 0.144197029 | 0.178025956 | | Free cholesterol in large LDL \|\| id:882 | MR Egger | 14 | 0.483221549 | 0.221836505 | 0.050047915 | | Free cholesterol in large LDL \|\| id:882 | Weighted median | 14 | 0.165139855 | 0.085257614 | 0.052751284 | | Free cholesterol in large LDL \|\| id:882 | Weighted mode | 14 | 0.015056322 | 0.369529691 | 0.968118659 | | Total lipids in large LDL \|\| id:883 | Inverse variance weighted | 17 | 0.183697128 | 0.129062069 | 0.15464228 | | Total lipids in large LDL \|\| id:883 | MR Egger | 17 | 0.50951585 | 0.204059106 | 0.024656026 | | Total lipids in large LDL \|\| id:883 | Weighted median | 17 | 0.125676086 | 0.079059536 | 0.111916305 | | Total lipids in large LDL \|\| id:883 | Weighted mode | 17 | 0.023892315 | 0.125114688 | 0.850956466 | | Concentration of large LDL particles \|\| id:884 | Inverse variance weighted | 17 | 0.181269946 | 0.130534771 | 0.164932595 | | Concentration of large LDL particles \|\| id:884 | MR Egger | 17 | 0.51930136 | 0.209966915 | 0.025832582 | | Concentration of large LDL particles \|\| id:884 | Weighted median | 17 | 0.113043707 | 0.079035862 | 0.152635605 | | Concentration of large LDL particles \|\| id:884 | Weighted mode | 17 | 0.025382543 | 0.109849435 | 0.820191875 | | Phospholipids in large LDL \|\| id:885 | Inverse variance weighted | 15 | 0.180109475 | 0.143171649 | 0.208392918 | | Phospholipids in large LDL \|\| id:885 | MR Egger | 15 | 0.589636961 | 0.221614725 | 0.019610675 | | Phospholipids in large LDL \|\| id:885 | Weighted median | 15 | 0.128023838 | 0.085166902 | 0.132784597 | | Phospholipids in large LDL \|\| id:885 | Weighted mode | 15 | 0.035268051 | 0.133118979 | 0.794919386 | | Total cholesterol in large VLDL \|\| id:886 | Inverse variance weighted | 7 | 0.722389087 | 1.283393897 | 0.573520669 | | Total cholesterol in large VLDL \|\| id:886 | MR Egger | 7 | -0.389140921 | 6.064221853 | 0.951321385 | | Total cholesterol in large VLDL \|\| id:886 | Weighted median | 7 | -0.027426912 | 0.097188007 | 0.777786556 | | Total cholesterol in large VLDL \|\| id:886 | Weighted mode | 7 | -0.022731355 | 0.117165125 | 0.852568858 | | Cholesterol esters in large VLDL \|\| id:887 | Inverse variance weighted | 8 | 0.835980474 | 1.022031075 | 0.413380064 | | Cholesterol esters in large VLDL \|\| id:887 | MR Egger | 8 | 0.278919497 | 3.348756204 | 0.936329878 | | Cholesterol esters in large VLDL \|\| id:887 | Weighted median | 8 | -0.001629876 | 0.092081445 | 0.985877878 | | Cholesterol esters in large VLDL \|\| id:887 | Weighted mode | 8 | -0.007476608 | 0.101462704 | 0.943319929 | | Free cholesterol in large VLDL \|\| id:888 | Inverse variance weighted | 9 | 0.740964329 | 1.075021746 | 0.490662685 | | Free cholesterol in large VLDL \|\| id:888 | MR Egger | 9 | -0.220201498 | 3.984352842 | 0.957470431 | | Free cholesterol in large VLDL \|\| id:888 | Weighted median | 9 | -0.021579358 | 0.09710973 | 0.824145559 | | Free cholesterol in large VLDL \|\| id:888 | Weighted mode | 9 | -0.031155363 | 0.109304349 | 0.782858594 | | Total lipids in large VLDL \|\| id:889 | Inverse variance weighted | 7 | 1.000470501 | 1.288588737 | 0.43750817 | | Total lipids in large VLDL \|\| id:889 | MR Egger | 7 | -2.914675268 | 5.918145876 | 0.643229445 | | Total lipids in large VLDL \|\| id:889 | Weighted median | 7 | -0.073379543 | 0.107194794 | 0.493631774 | | Total lipids in large VLDL \|\| id:889 | Weighted mode | 7 | -0.071941833 | 0.109136829 | 0.534240676 | | Height \|\| id:89 | Inverse variance weighted | 321 | -0.115878195 | 0.037717592 | 0.002124456 | | Height \|\| id:89 | MR Egger | 321 | -0.088414549 | 0.100245744 | 0.378452747 | | Height \|\| id:89 | Weighted median | 321 | -0.110570938 | 0.05763472 | 0.055050437 | | Height \|\| id:89 | Weighted mode | 321 | -0.082892229 | 0.098701758 | 0.401633373 | | Concentration of large VLDL particles \|\| id:890 | Inverse variance weighted | 8 | 0.490305266 | 0.509336946 | 0.335731027 | | Concentration of large VLDL particles \|\| id:890 | MR Egger | 8 | -0.787544719 | 1.706222318 | 0.660648611 | | Concentration of large VLDL particles \|\| id:890 | Weighted median | 8 | -0.032846126 | 0.106913712 | 0.758675248 | | Concentration of large VLDL particles \|\| id:890 | Weighted mode | 8 | -0.065421671 | 0.116485095 | 0.591886023 | | Phospholipids in large VLDL \|\| id:891 | Inverse variance weighted | 7 | 0.753017294 | 1.338664462 | 0.573765973 | | Phospholipids in large VLDL \|\| id:891 | MR Egger | 7 | 0.007452388 | 5.486925211 | 0.99896883 | | Phospholipids in large VLDL \|\| id:891 | Weighted median | 7 | -0.041632202 | 0.102561022 | 0.684796857 | | Phospholipids in large VLDL \|\| id:891 | Weighted mode | 7 | -0.021633442 | 0.108283322 | 0.84824738 | | Triglycerides in large VLDL \|\| id:892 | Inverse variance weighted | 7 | 0.720272362 | 1.320239713 | 0.585367185 | | Triglycerides in large VLDL \|\| id:892 | MR Egger | 7 | -1.350656617 | 5.290399429 | 0.808658126 | | Triglycerides in large VLDL \|\| id:892 | Weighted median | 7 | -0.054742347 | 0.101415982 | 0.589348567 | | Triglycerides in large VLDL \|\| id:892 | Weighted mode | 7 | -0.075878239 | 0.105805776 | 0.500236293 | | 18:2, linoleic acid (LA) \|\| id:893 | Inverse variance weighted | 10 | 0.473982148 | 0.327713579 | 0.148084523 | | 18:2, linoleic acid (LA) \|\| id:893 | MR Egger | 10 | 1.539736001 | 0.751259416 | 0.074561442 | | 18:2, linoleic acid (LA) \|\| id:893 | Weighted median | 10 | -0.016458606 | 0.082830136 | 0.84249499 | | 18:2, linoleic acid (LA) \|\| id:893 | Weighted mode | 10 | -0.040937188 | 0.080289552 | 0.622410423 | | Body fat \|\| id:999 | Inverse variance weighted | 9 | -3.778876005 | 2.94195583 | 0.198974939 | | Body fat \|\| id:999 | MR Egger | 9 | -43.19265833 | 12.98382681 | 0.012649048 | | Body fat \|\| id:999 | Weighted median | 9 | -0.595719688 | 0.26897779 | 0.026776941 | | Body fat \|\| id:999 | Weighted mode | 9 | -0.84908266 | 0.358189454 | 0.045212192 | --- # Agent Instructions This documentation is published with GitBook. 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